Results 321 to 330 of about 2,892,311 (358)

The taxonomy of binding sites in proteins

Molecular and Cellular Biochemistry, 1978
Conservation of polypeptide fold and mode of ligand binding is frequently found within proteins of related function. Examples illustrating this phenomenon are taken from NAD linked enzymes, nucleotide binding proteins, polysaccharide binding proteins, heme binding proteins and enzymes with essential Fe--S complexes or zinc atoms.
Michael G. Rossmann, Patrick Argos
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Binding sites for calcium on tubulin

Biochemistry, 1977
Calcium ions can inhibit the in vitro assembly of microtubules and, therefore, may play a role in the regulation of microtubule formation in vivo. In order to test the validity of this hypothesis; the interaction between calcium and pruified brain microtubular protein has been investigated by standard binding assays.
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A citrate-binding site in calmodulin

Journal of Molecular Recognition, 1998
Calmodulin (CaM) is a major Ca2+ messenger which, upon Ca2+ activation, binds and activates a number of target enzymes involved in crucial cellular processes. The dependence on Ca2+ ion concentration suggests that CaM activation may be modulated by low-affinity Ca2+ chelators.
Karol A. Muszkat, Gideon Fleminger, Miriam Eisenstein, Tova Neufeld   +3 more
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Localization of the Chaperone Binding-Site

Biochemical and Biophysical Research Communications, 1993
The hypothesis derived from models of the multi-oligomeric chaperone complex suggests that partially denatured proteins bind in a central cavity in the aggregate. To test this hypothesis, the molecular chaperone, alpha crystallin, was bound to partially denatured forms of gamma crystallin, and the binding site was visualized by immunogold localization.
Daniel L. Boyle, Larry J. Takemoto, S. Gopalakrishnan   +2 more
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Melatonin Binding Sites

1993
Publisher Summary Melatonin is synthesized in vertebrate photoreceptors and constitutes the major known secretory product of the pineal gland. The synthesis and secretion of melatonin are photically regulated, restricted to the hours of darkness and inhibited by exposure to light during the night.
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MEASUREMENT OF TESTOSTERONE BINDING SITES

Acta Endocrinologica, 1970
ABSTRACT A Sephadex assay technique, in use in our laboratory for the study of steroid-protein interactions, allows expression of the molar concentration of a testosterone-binding component of human serum of high binding affinity in terms of the molar concentration of testosterone-binding sites: examples with model calculations are provided ...
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Three binding sites on t-PA: Lysine binding sites (LBS), fibrinogen) binding site and a site to bind to LBS

Fibrinolysis, 1989
A. Takeda, Yumiko Takada, T. Urano, K. Sakakibara   +3 more
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The Ribosome Binding Site Calculator

2011
The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA transcript.
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Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Kimberly D Miller, Quinn T Ostrom, Carol Kruchko Ba   +2 more
exaly  

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Shanu Modi   +2 more
exaly