Results 191 to 200 of about 1,627,769 (335)

Indirect identification of genomic G-quadruplexes via a small protein probe that specifically recognizes C-rich single-stranded DNA. [PDF]

Nucleic Acids Res
Chen JN, Xie ML, Yan JY, Cai TT, Ding YW, He TX, Wang J, Huang J, Zheng KW.   +8 more
europepmc   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

DSCA-HLAII: A dual-stream cross-attention model for predicting peptide-HLA class II interaction and presentation. [PDF]

PLoS Comput Biol
Yan K, Yu H, Chen S, Shaytan AK, Liu B, Wang Y.   +5 more
europepmc   +1 more source

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Viral glycoprotein-mediated entry and antibody-mediated immunity in HIV-1 and SARS-CoV-2 infection. [PDF]

Front Immunol
Grunst MW, Li W, Mothes W.
europepmc   +1 more source

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine.

Blood, 2015
G. Gilbert, V. Novakovic, Jialan Shi, J. Rasmussen, S. Pipe   +4 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Reactivity of Antibodies Immobilized on Gold Nanoparticles: Fluorescence Quenching Study. [PDF]

Molecules
Sotnikov DV, Agapov AS, Zherdev AV, Dzantiev BB.   +3 more
europepmc   +1 more source

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Journal of Histochemistry and Cytochemistry, 1981
S. Hsu, L. Raine, H. Fanger
semanticscholar   +1 more source

Using structural fragments to design antibody binding sites

, 2018
Antibodies are an essential part of the immune system. They are able to attain high specificity and affinity to almost any antigen, and through their modularity make a robust framework for protein engineering. As a result, development of therapeutic antibodies has grown rapidly and they now account for the majority of revenue in the sales of new bio ...
openaire   +1 more source