Results 271 to 280 of about 1,627,769 (335)

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source

An integrated in silico and in vitro genotype to phenotype pipeline to predict and characterise new RSV F site zero escape mutants

Mosscrop L, Gerardi V, Kose S, Talts T, Thomas C, Paschos K, Brown J, Williams T, Skinner M, de Lusignan S, Zambon M, Bravi B, Tregoning J.   +12 more
europepmc   +1 more source

Discovery and molecular mechanism of potent neutralizing antibody from humanized mice with respiratory syncytial virus. [PDF]

PLoS Pathog
Zhang Z, Feng R, Zhang L, Yang Q, Chen X, Wang X, Nie C, Peng W, Wang X, Zhu L, Guo Y, Sun Z.   +11 more
europepmc   +1 more source

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

Advanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa, Ana B. Carneiro, Filipa Lebre, João Meneses, Alar Ainla, Cacilda Moura, Ernesto Alfaro‐Moreno, Ana R. Ribeiro   +7 more
wiley   +1 more source

A Bifunctional Antibody Conjugate for Marking the Location of DNA Binding Proteins on DNA Fibers. [PDF]

ACS Omega
Pokharel D, Shaik A, Gali H, Ling C, Bellani MA, Seidman MM.   +5 more
europepmc   +1 more source

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Fab N-Glycosylation in IgG: Implications in Physiological and Pathological Immune Regulation. [PDF]

Biomolecules
Chen S, Yu F, Huang B, Liang G, Xu J, Lin Y, Xu Q.   +6 more
europepmc   +1 more source

EBNA1 SUMOylation by PIAS1 suppresses EBV lytic replication and enhances episome maintenance. [PDF]

mBio
Sugiokto FG, Zhang K, Maharjan Y, Li R.
europepmc   +1 more source

Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements. [PDF]

Epigenetics Chromatin
Maksimenko O, Klimenko N, Salloum G, Umnova A, Kyrchanova O, Melnikova L, Georgiev P.   +6 more
europepmc   +1 more source