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Rhizoxin binding to tubulin at the maytansine-binding site

Biochimica et Biophysica Acta (BBA) - General Subjects, 1987
The binding of rhizoxin, a potent inhibitor of mitosis and in vitro microtubule assembly, to porcine brain tubulin was studied. Tubulin possesses one binding site for rhizoxin per molecule with a dissociation constant (Kd) of 1.7.10(-7) M. Ansamitocin P-3, a homologue of maytansine, was a competitive inhibitor of rhizoxin binding, with an inhibition ...
M, Takahashi   +5 more
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MEASUREMENT OF TESTOSTERONE BINDING SITES

Acta Endocrinologica, 1970
ABSTRACT A Sephadex assay technique, in use in our laboratory for the study of steroid-protein interactions, allows expression of the molar concentration of a testosterone-binding component of human serum of high binding affinity in terms of the molar concentration of testosterone-binding sites: examples with model calculations are provided ...
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The Ribosome Binding Site Calculator

2011
The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA transcript.
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Melatonin binding sites: Are they receptors?

Molecular and Cellular Endocrinology, 1992
D J, Kennaway, H M, Hugel
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Solubilization of the dihydropicrotoxinin binding sites

European Journal of Pharmacology, 1980
W C, Davis, M K, Ticku
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