Results 341 to 350 of about 8,324,980 (383)
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Current Opinion in Biotechnology, 1992
Metal ions have a role in a variety of important functions in proteins including protein folding, assembly, stability, conformational change, and catalysis. The presence or absence of a given metal ion is crucial to the conformation or activity of over one third of all proteins.
Elizabeth D. Getzoff +2 more
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Metal ions have a role in a variety of important functions in proteins including protein folding, assembly, stability, conformational change, and catalysis. The presence or absence of a given metal ion is crucial to the conformation or activity of over one third of all proteins.
Elizabeth D. Getzoff +2 more
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Benzodiazepine-Binding Site and Gaba-Binding Site
1983There is a body of experimental evidence to suggest that the benzodiazepine-binding site, the GABA-binding site and the chloride ionophore are functionally correlated. To elucidate this issue, the interactions among these components in both membrane-bound state and soluble state are examined.
Eric A. Barnard, Li-Ren Chang
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Journal of Neurochemistry, 1988
Abstract: The distribution and characterization of specific melatonin binding sites were studied using 125I‐melatonin. Autoradiography revealed only three sites of specific melatonin binding in brain: the suprachiasmatic nuclei, the median eminence, and the small part of choroid plexus at the caudal end of the fourth ventricle.
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Abstract: The distribution and characterization of specific melatonin binding sites were studied using 125I‐melatonin. Autoradiography revealed only three sites of specific melatonin binding in brain: the suprachiasmatic nuclei, the median eminence, and the small part of choroid plexus at the caudal end of the fourth ventricle.
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Binding Sites for Ethylene [PDF]
, 1984 This article describes recent work on the characterisation and purification of an ethylene binding site complex (EBS) derived from developing cotyledons of Phaseolus vulgaris L.
C. J. R. Thomas +3 more
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The binding site for C1q on IgG [PDF]
Nature, 1988 In humoral defence, pathogens are cleared by antibodies acting as adaptor molecules: they bind to antigen and trigger clearance mechanisms such as phagocytosis, antibody-dependent cell-mediated cytotoxicity and complement lysis. The first step in the complement cascade is the binding of C1q to the antibody.
Alexander R. Duncan, Greg Winter
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On the receptor binding site of relaxins
International Journal of Peptide and Protein Research, 1988Relaxin plays a critical role in viviparity and has recently been implicated as a hormone of oviparity as well. In most mammals relaxin causes the widening of the birth canal during parturition and suppresses uterine motility during pregnancy. Relaxins isolated from several species have shown a great deal of sequence variability, and speculations ...
Christian Schwabe, Erika E. Büllesbach
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Mitochondrial Binding Sites for Triiodothyronine
Endocrinology, 1978Metabolic effects upon rat liver mitochondria have been observed by others within 2 min of injection of massive amounts of L-T4. Reported here is the subcellular distribution of 2--5 ng high specific activity [125I]L-T3 2 min after ip injection with and without a loading dose of 30 micrograms unlabeled T3.
Roger L. Greif, Denise A. Sloane
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A Binding Site for Chlorambucil on Metallothionein
Biochemistry, 1996It is of interest to test the hypothesis that induced metallothionein (MT) acts in acquired drug resistance by covalent sequestration. In this study MT was incubated in vitro with chlorambucil (CHB) under conditions where only 1:1 covalent adducts were formed.
Joseph Zaia +6 more
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Metal-binding sites in proteins
Current Opinion in Biotechnology, 1991A dramatic increase in the number of solved metalloprotein structures and recent breakthroughs in structural analysis have provided a sufficiently detailed understanding of the structural chemistry of some metal-binding sites to allow successful design.
Elizabeth D. Getzoff +2 more
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1987
An account is given of the purification of the ethylene binding protein from developing cotyeldons of Phaseolus vulgaris. A correlation has been demonstrated between ethylene binding and sensitivity to the hormone in epicotyls of Pisum sativum. As this tissue also metabolises ethylene, this system could provide evidence for the hypothesis that ethylene
R. A. N. Williams +4 more
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An account is given of the purification of the ethylene binding protein from developing cotyeldons of Phaseolus vulgaris. A correlation has been demonstrated between ethylene binding and sensitivity to the hormone in epicotyls of Pisum sativum. As this tissue also metabolises ethylene, this system could provide evidence for the hypothesis that ethylene
R. A. N. Williams +4 more
openaire +2 more sources