Results 181 to 190 of about 62,783 (309)

metaIVP: an integrative metavirome focused metagenomic processing pipeline. [PDF]

BMC Methods
Sahu K, Yao Q.
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Reply to Li & Zhang: Adaptive evolution of stop-loss RNA editing in <i>Fusarium graminearum</i>. [PDF]

Proc Natl Acad Sci U S A
Du Y, Wang Q, Liu H.
europepmc   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source

Rapid Species-Level Classification of Urinary Pathogens from Raw LC-MS/MS Signals Using Machine Learning. [PDF]

Anal Chem
Pelletier SJ, Lacombe-Rastoll A, Roux-Dalvai F, Leclercq M, Gotti C, Bérubé E, Bories P, Thibeault MÈ, Bekker-Jensen DB, Bache N, Bromirski M, Isabel S, Precioso F, Droit A.   +13 more
europepmc   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Calibrating tetranucleotide-frequency distances for metagenomic binning with right-skewed distribution models. [PDF]

Bioinform Adv
Hajjaji O, Al-Soudy AS, Daoud R, Benhida R, Mokhtar MM.   +4 more
europepmc   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Community-driven updates for comprehensive long-read metagenomics and enhanced binning in nf-core/mag v5. [PDF]

Bioinformatics
Alvarez Saravia D, Rosenbaum A, Straub D, Downie J, Borry M, Fedewa G, Hübner A, Lundin D, Yepes-García J, McDonald J, Nahnsen S, Köhn L, Uribe-Paredes R, Navarrete MA, Warinner C, nf-core community, Fellows Yates JA.   +16 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source