VirBinn improves viral genome binning from metagenomic Hi-C through graph diffusion. [PDF]
Wang S, Du Y.
europepmc +1 more source
Multiphoton Quantum Reservoirs For Robust Multidimensional Computing
Projective measurements reveal hidden multidimensional quantum networks within classical multiphoton fields, enabling robust quantum reservoirs for room‐temperature quantum simulation, prediction, and information processing. These networks transform noisy classical photonic platforms into scalable quantum computational architectures.
Mingyuan Hong +10 more
wiley +1 more source
DCVBin: a novel binning method for single-sample metagenomes based on DNA language model and variational autoencoder. [PDF]
Wang J +6 more
europepmc +1 more source
STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang +9 more
wiley +1 more source
A genomic catalog of the mouse gut virome reveals features associated with ageing. [PDF]
Kim HJ +11 more
europepmc +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Clifti-GPT: privacy-preserving federated fine-tuning and transferable inference of foundation models on clinical single-cell data. [PDF]
Bakhtiari M +5 more
europepmc +1 more source
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source
EMORe: Motion-Robust 5D MRI Reconstruction via Expectation-Maximization-Guided Binning Correction and Outlier Rejection. [PDF]
Arshad SM +5 more
europepmc +1 more source
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source

