Results 41 to 50 of about 44,005 (262)

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu   +17 more
wiley   +1 more source

Statistics on Lattice Walks and q-Lassalle Numbers [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2015
This paper contains two results. First, I propose a $q$-generalization of a certain sequence of positive integers, related to Catalan numbers, introduced by Zeilberger, see Lassalle (2010).
Lenny Tevlin
doaj   +1 more source

An upper bound on binomial coefficients in the de Moivre – Laplace form

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2022
We provide an upper bound on binomial coefficients that holds over the entire parameter range an whose form repeats the form of the de Moivre – Laplace approximation of the symmetric binomial distribution.
Sergey V. Agievich
doaj   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

open access: yesAdvanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang   +3 more
wiley   +1 more source

Can we detect Gaussian curvature by counting paths and measuring their length?

open access: yesRevista Integración, 2020
The aim of this paper is to associate a measure for certain sets of paths in the Euclidean plane R2 with fixed starting and ending points. Then, working on parameterized surfaces with a specific Riemannian metric, we define and calculate the integral of ...
Leonardo A. Cano G., Sergio A. Carrillo
doaj  

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

open access: yesAdvanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

On divisibility of binomial coefficients

open access: yesDiscrete Mathematics, 1994
Let \(p\) be a prime and \(A(n,p)\) the \(p^ n\times p^ n\)-matrix with entries \(a_{ij}= \left(\begin{smallmatrix} i\\ j\end{smallmatrix}\right)\text{ mod }p\) for \(0\leq i,j< p^ n\). It is shown that \(A(n,p)\) is the \(n\)-fold tensor product of \(A(1,p)\) with itself. As an application a short proof is given that there are precisely \(\left(\begin{
openaire   +2 more sources

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

open access: yesAdvanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li   +6 more
wiley   +1 more source

Many identities from one

open access: yesLe Matematiche, 1996
We specialise an ingeniously contrived identity to obtain a plethora of startling combinatorial identities. Limiting cases include well known evaluations of ζ(2), ζ(4) and ζ(6).
Chu Wenchang
doaj  

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