Results 61 to 70 of about 46,762 (263)
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
Advanced Science, EarlyView.A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li +9 more
wiley +1 more source
Axioms, 2019 The aim of this paper is to construct generating functions for new families of combinatorial numbers and polynomials. By using these generating functions with their functional and differential equations, we not only investigate properties of these new ...
Irem Kucukoglu +2 more
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Harmonic number identities via polynomials with r-Lah coefficients
Comptes Rendus. Mathématique, 2020 In this paper, polynomials whose coefficients involve $r$-Lah numbers are used to evaluate several summation formulae involving binomial coefficients, Stirling numbers, harmonic or hyperharmonic numbers.
Kargın, Levent, Can, Mümün
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Advanced Science, EarlyView.In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
Advanced Science, EarlyView.Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
Binomial Coefficients and Lucas Sequences
Journal of Number Theory, 2002 Let sequences \(\{u_n\}_{n\geq 0}\) and \(\{v_n\}_{n\geq 0}\) be defined by \(u_n= \frac{a^n-b^n}{a-b}\), \(v_n= a^n+b^n\) where \(a,b\) are integers such that \(a>|b|\). (Such sequences are Lucas sequences such that the associated quadratic polynomial has integer roots.
Flammenkamp, Achim, Luca, Florian
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A divisibility property of binomial coefficients viewed as an elementary sieve
International Journal of Mathematics and Mathematical Sciences, 1981 The triangular array of binomial coefficients 012301111212131331… is said to have undergone a j-shift if the r-th row of the triangle is shifted rj units to the right (r=0,1,2,…). Mann and Shanks have proved that in a 2-shifted array a column number c>
Richard H. Hudson, Kenneth S. Williams
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Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2013 The correctness of equality which gives the combinatorial expression for the sum of the weighted equal powers of members of an arithmetical progression is found out.
Alexander I Nikonov
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DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction
Advanced Science, EarlyView.Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li +3 more
wiley +1 more source
The update exposition of the components organisig the sum of weighted equal powers
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012 The sum of the weighted equal powers with natural bases and parameters is organized of components, which are independent or dependent on weight coefficients.
Alexander I Nikonov
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