Results 51 to 60 of about 6,578 (291)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Bio-logging science: sensing beyond the boundaries [PDF]

open access: yes, 2004
Bio-logging has emerged as a tool in animal biology much as genomics has emerged as a tool in the study of cellular and organ function. Bio-logging is certain to increase in its importance and to influence the way we study events and processes that are ...
Boyd,Ian L.   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Development of Data Logger Separator for Bio-Logging of Wild Seabirds

open access: yesJournal of Robotics and Mechatronics, 2021
The bio-logging technique is extensively used in the fields of ecology and ethology, wherein a data logger, such as a sensor or camera, is attached to the target animal’s body to collect the required data. In this method, the efficiency of recovery of the data logger is not ideal.
Takuma Abe   +7 more
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Tools for integrating inertial sensor data with video bio-loggers, including estimation of animal orientation, motion, and position

open access: yesAnimal Biotelemetry, 2021
Bio-logging devices equipped with inertial measurement units—particularly accelerometers, magnetometers, and pressure sensors—have revolutionized our ability to study animals as necessary electronics have gotten smaller and more affordable over the last ...
David E. Cade   +10 more
doaj   +1 more source

Towards a Wearer-Centred Framework for Animal Biotelemetry [PDF]

open access: yes, 2016
The emerging discipline of Animal-Computer Interaction (ACI) aims to understand the relation between animals and technology in naturalistic settings, to design technology that can support animals in different contexts and to develop user-centred research
Mancini, Clara   +2 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Behavioural networks: a new methodology to study birds’ habits [PDF]

open access: yesNetwork Biology, 2019
We introduce here a new methodology, named Behavioural Networks (BeNe), to thoroughly analyze birds’ habits in space and time. Behavioural Networks are based on GIS technologies, association rules and network capabilities, all applied to GPS data.
Alessandro Ferrarini   +2 more
doaj  

Overall Dynamic Body Acceleration in Straw-Colored Fruit Bats Increases in Headwinds but Not With Airspeed

open access: yesFrontiers in Ecology and Evolution, 2019
Atmospheric conditions impact how animals use the aerosphere, and birds and bats should modify their flight to minimize energetic expenditure relative to changing wind conditions.
M. Teague O'Mara   +18 more
doaj   +1 more source

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