Results 41 to 50 of about 1,382,457 (281)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Bio-Medical Library Bulletin, No. 51 (1977-04) [PDF]
, 1977 Bio-Medical Library. (1977). Bio-Medical Library Bulletin, No. 51 (1977-04).
Bio-Medical Library
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Bio-inspired nano rotor investigation based on UVLM
Biosurface and Biotribology, 2019 Nano rotor is of great value in military and civilian applications. Due to its nano size, it works at an ultra-low Reynolds number and aerodynamic performance deteriorates dramatically.
Zhao Shanyong +4 more
doaj +1 more source
Materials & DesignIntelligent piezoresistive health monitoring systems integrate advanced nanocomposite architectures with precise algorithmic analysis for real-time physiological assessment. However, existing works often prioritize high sensitivity at the expense of strain tolerance and require complex fabrication procedures.
Ke-Yu Yao +10 more
openaire +2 more sources
Bio-Medical Library Bulletin, No. 100 (1989-04) [PDF]
, 1989 Bio-Medical Library. (1989). Bio-Medical Library Bulletin, No. 100 (1989-04).
Bio-Medical Library
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Resource-efficient bio-inspired visual processing on the hexapod walking robot HECTOR.
PLoS ONE, 2020 Emulating the highly resource-efficient processing of visual motion information in the brain of flying insects, a bio-inspired controller for collision avoidance and navigation was implemented on a novel, integrated System-on-Chip-based hardware module ...
Hanno Gerd Meyer +6 more
doaj +1 more source
Bio-Medical Library Bulletin, No. 54 (1977-12) [PDF]
, 1977 Bio-Medical Library. (1977). Bio-Medical Library Bulletin, No. 54 (1977-12).
Bio-Medical Library
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source