Results 61 to 70 of about 661,511 (263)

Modelo de ciudades educadoras en red y de red de ciudades educadoras para el Valle del Cauca, como estrategia del humanismo económico [PDF]

open access: yes, 2008
The goal of the document is to present how to articulate a new model of human development since the territorial strategy educating city. It is hoped that “the city in partnership with the university” are the starting point for developing principles-based
Garzón Castro, Hugo   +1 more
core   +1 more source

Nuevos registros de serpientes en el Chaco biogeográfico de Argentina [PDF]

open access: yes, 2023
Considerando que revisamos el material disponible de la especie en Argentina, los nuevos registros aquí aportados, constituyen los más australes conocidos para la especie.
Acosta, Luis   +6 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Gobierno, Región, Gestión y Territorio:El Caso de la Región del Bío-Bío.

open access: yesRevista Enfoques, 2007
This document presents the results, for the Bío Bío region, of the “Regional Management Model Analysis” study. The central objective of this study was to analyze the Regional Management System and to elaborate proposals for the improvement of the ...
Pablo Monje Reyes, Marcela Ferrer Lues
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Evaluación arqueológica de los sitios de producción agrícola del área arqueológica Monte Puñay, provincias de Cañar y Chimborazo. [PDF]

open access: yes, 2019
La investigación propuesta plantea: evaluar arqueológicamente los sitios de producción agrícola del área arqueológica Monte Puñay, provincias de Cañar y Chimborazo; para ello se revisaron fuentes etnohistóricas y etnográficas que permitieron documentar ...
González Curillo, Karina Abigail
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Caracterización fisicoquímica, propiedades nutricionales y determinación del poder antioxidante e insecticida de extractos de cúrcuma (Cúrcuma longa), cultivada en una bio-región del Valle del Cauca. [PDF]

open access: yes, 2018
La Curcuma longa es una planta de origen hindú, pertenece a la familia de las zingiberaceas y actualmente se cultiva en Colombia, esta planta ha sido objeto de varios estudios por su carácter nutricional y medicinal, se ha implementado como cultivo de ...
Nobile Correa, Diana Paola   +2 more
core  

Comparación de la actividad de las transaminasas GOT y GPT en Ameghinomya antiqua (MOLLUSCA: VENERIDAE) en dos sectores de la Región del Bïo-Bío [PDF]

open access: yes
In mollusk, transaminases Glutamic Piruvic (GPT) and Glutamic Oxalacetic (GOT) have an importantfunction in the osmorregulatory processes, providing free aminoacids.
Constanzo A., José   +1 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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