Total Syntheses of (+)-Hyperbeanols A-C, (+)-Hyperpatulol A, and (-)-Hypercohone G, as Well as Structure Revision of Hyperpatulol A, and Hyperbeanol B. [PDF]
Liu X +6 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Correction: Fermentation and storage characteristics of "Fuji" apple juice using <i>Lactobacillus acidophilus, Lactobacillus casei</i> and <i>Lactobacillus plantarum</i>: microbial growth, metabolism of bioactives and <i>in vitro</i> bioactivities. [PDF]
Frontiers Production Office.
europepmc +1 more source
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang +15 more
wiley +1 more source
Integrative metabolomics using untargeted UHPLC-MS/MS and chemometrics identifies optimal maturity stage of <i>Moringa oleifera</i> leaves from Kuala Terengganu, Malaysia. [PDF]
Azlan UK +13 more
europepmc +1 more source
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv +13 more
wiley +1 more source
One-Step Ultrasound-Assisted Synchronous Extraction of Polysaccharides and Polyphenols from Blue Honeysuckle Berries: Structural Characteristics and Associated Bioactivities. [PDF]
Gao R, Zhang L, Huo J, Sui X, Zhang Y.
europepmc +1 more source
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun +10 more
wiley +1 more source
Bioactive Polysaccharides from Blue Honeysuckle Berries: Structural Properties and Digestive Enzyme Inhibition Activities. [PDF]
Ding N, Sun J, Li J, Huo J, Zhang Y.
europepmc +1 more source
To explore the impact of nanosizing on pesticide biointeractions, a 7‐nm (average) emamectin benzoate nanopesticide without nanocarriers or surfactants is fabricated via HOAc‐mediated disaggregation. Nanosizing enhances bioactivity against Megalurothrips usitatus and Meloidogyne enterolobii and improves plant penetration.
Jiaqi Wei +11 more
wiley +1 more source

