Results 91 to 100 of about 268,265 (293)

High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity

Environment International, 2020
High-throughput and computational tools provide a new opportunity to calculate combined bioactivity of exposure to diverse chemicals acting through a common mechanism.
Susanna H. Wegner, Caroline L. Pinto, Caroline L. Ring, John F. Wambaugh   +3 more
doaj   +1 more source

Bioactivity in Whey Proteins Influencing Energy Balance [PDF]

, 2012
Peer-reviewedObesity develops due to energy (food) intake exceeding energy expenditure. Nutrients that reduce the positive energy balance are thus being considered as therapies to combat obesity.
Cotter, Paul D., Korpela, Riitta, McAllan, Liam, Nilaweera, Kanishka, Roche, Helen M.   +4 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Structural/Functional Matches and Divergences of Phytoprostanes and Phytofurans with Bioactive Human Oxylipins

Antioxidants, 2018
Structure-activity relationship (SAR) constitutes a crucial topic to discover new bioactive molecules. This approach initiates with the comparison of a target candidate with a molecule or a collection of molecules and their attributed biological ...
Sonia Medina, Ángel Gil-Izquierdo, Thierry Durand, Federico Ferreres, Raúl Domínguez-Perles   +4 more
doaj   +1 more source

Bioactive ceramic-reinforced composites for bone augmentation [PDF]

, 2010
Biomaterials have been used to repair the human body for millennia, but it is only since the 1970s that man-made composites have been used. Hydroxyapatite (HA)-reinforced polyethylene (PE) is the first of the ‘second-generation’ biomaterials that have ...
Bonfield W., Bonfield W., Charnley J., Downes R. N., Doyle C., Goldenberg R. A., Hao L., Hao L., Huang J., Huang J., Jones L. C., K. E. Tanner, Kobayashi A., Parkhill C., Revell P. A., Sarmiento A., Tanner K. E., Tanner K. E., Törmälä P., Wang M., Zhang Y.   +20 more
core   +2 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

New UHPLC-QqQ-MS/MS Method for the Rapid and Sensitive Analysis of Ascorbic and Dehydroascorbic Acids in Plant Foods

Molecules, 2019
A new method using ultra high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UHPLC-QqQ-MS/MS) methodology was developed for the determination of ascorbic acid (AA) and dehydroascorbic acid (DHAA) contents in liquid ...
Nieves Baenas, Francisco J. Salar, Raúl Domínguez-Perles, Cristina García-Viguera   +3 more
doaj   +1 more source

Ex-vivo perfusion bioassay : an excellent technique to measure the bioactivity of inhalable insulin coated microcrystals [PDF]

, 2002
Purpose: To measure the bioactivity of inhalable insulin coated microcrystals using a perfusion bioassay that measures its vasodilatory effect on smooth muscle arterial tissue.
Brown, Amanda J., Coleman, Jamie, Flores, Maria, Hillier, Chris, Moore, Barry, Parker, Marie-Claire, Partridge, Johann, Ross, Alistair, Stevens, Howard   +8 more
core  

Modulation of Arabidopsis and monocot root architecture by CLAVATA3/EMBRYO SURROUNDING REGION 26 peptide [PDF]

, 2015
Plant roots are important for a wide range of processes, including nutrient and water uptake, anchoring and mechanical support, storage functions, and as the major interface with the soil environment.
Brigitte Van, Charlie Hodgman, Chun-lin Shi, De Cotte, Ive De Smet, Lam Dai Vu, Melinka A. Butenko, Nathan Czyzewicz   +7 more
core   +2 more sources

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source