Results 101 to 110 of about 268,265 (293)
MMsPred: a bioactivity and toxicology predictive system [PDF]
, 2010 In the last decade, the development and use of new methods in combinatorial chemistry and high-throughput screening has dramatically increased the number of known biologically active compounds.
Joel Masciocchi +6 more
core +2 more sources
Advanced Functional Materials, EarlyView.This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Visualizing bioactive ceramides
Chemistry and Physics of Lipids, 2018 In the last 30 years, ceramides have been found to mediate a myriad of biological processes. Ceramides have been recognized as bioactive molecules and their metabolizing enzymes are attractive targets in cancer therapy and other diseases. The molecular mechanism of action of cellular ceramides are still not fully established, with insights into roles ...
Daniel Canals +2 more
openaire +3 more sources
International Journal of Molecular Sciences, 2022 Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...]
openaire +2 more sources
4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles
Advanced Functional Materials, EarlyView.Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner +12 more
wiley +1 more source
FoodsFood sustainability through traditional food production and the reuse of food by-products is one of the characteristics most valued by consumers. The production of Iberian ham is linked to the vaporization and sustainability of the dehesa and the ...
Eva Bruna-García +2 more
doaj +1 more source
SnapShot: Bioactive Lysophospholipids
Cell, 2012 Lysophosphatidic acid (LPA; monoacyl-glycerol-3-phosphate) and sphingosine 1-phosphate (S1P) are bioactive lysophospholipids that regulate critical biological functions and disease processes. LPA and S1P act on distinct G protein-coupled receptors (GPCRs) that initiate multiple signaling cascades in many cell types.
Moolenaar, Wouter H., Hla, Timothy
openaire +2 more sources
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Frontiers in Microbiology, 2017 Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma +7 more
doaj +1 more source
PLoS ONE, 2020 BackgroundColostrum, the milk produced during first few days after birth, is rich in immunoglobulins, antimicrobial peptides & growth factors. Multiple clinical trials using bovine colostrum are ongoing but with no assessment of test product bioactivity ...
Raymond J Playford +2 more
doaj +1 more source