Results 91 to 100 of about 3,487,707 (291)

Diverse biological effects of glycosyltransferase genes from Tartary buckwheat [PDF]

, 2019
Background: Tartary buckwheat (Fagopyrum tataricum) is an edible cereal crop whose sprouts have been marketed and commercialized for their higher levels of anti-oxidants, including rutin and anthocyanin. UDP-glucose flavonoid glycosyltransferases (UFGTs)
Chen, Hui, Deng, Renyu, Dong, Qixin, Huang, Yunji, Li, Chenglei, Li, Qi, Lv, Bingbing, Shi, Guanlan, Shi, Jiaqi, Stael, Simon, Wu, Qi, Yao, Panfeng, Zhao, Haixia   +12 more
core   +2 more sources

Computational Evaluation of ADMET Properties and Bioactive Score of Compounds from Encephalartos ferox [PDF]

Pharmacognosy Journal, 2020
Tsolanku Sidney Maliehe, Phakamani Hopewell Tsilo, Jabulani Siyabonga Shandu   +2 more
openaire   +1 more source

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

Data-driven score tuning for ChooseLD: A structure-based drug design algorithm with empirical scoring and evaluation of ligand–protein docking predictability

Biophysics and Physicobiology
Computerized molecular docking methodologies are pivotal in in-silico screening, a crucial facet of modern drug design. ChooseLD, a docking simulation software, combines structure- and ligand-based drug design methods with empirical scoring.
Akihiro Masuda, Daichi Sadato, Mitsuo Iwadate   +2 more
doaj   +1 more source

Computational identification of potential dengue RdRp inhibitors through docking, ADMET, and molecular dynamics

In Silico Research in Biomedicine
Dengue fever, caused by the dengue virus (DENV), remains a significant global health threat due to the lack of specific antiviral treatments or vaccines.
Hari Priya Narra, Venkata Monika Sarvani Atmakuri, Geethanjali Mandalapu, Shraddha Bhaskarani, Jyotsna Bandi, Garlapati Sujitha, Sudheer Kumar Katari, Anand Kumar Nelapati   +7 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches

Computational and Structural Biotechnology Journal
We developed a bio-cheminformatics method, exploring disease inhibition mechanisms using machine learning-enhanced quantitative structure-activity relationship (ML-QSAR) models and knowledge-driven neural networks.
Ajay Manaithiya, Ratul Bhowmik, Satarupa Acharjee, Sameer Sharma, Sunil Kumar, Mohd. Imran, Bijo Mathew, Seppo Parkkila, Ashok Aspatwar   +8 more
doaj   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]

, 2018
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik, Enemark, Heidi L., López-Muñoz, Rodrigo, Peña-Espinoza, Miguel, Simonsen, Henrik T., Thamsborg, Stig M., Valente, Angela H., Williams, Andrew R.   +7 more
core   +4 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source