Results 81 to 90 of about 18,395 (198)
Responsive Materials, EarlyView.Carbon dots are emerging as versatile electrochemiluminescent nanomaterials whose structure, surface states, and interfacial design jointly determine ECL pathways and performance. This review highlights how mechanistic understanding and materials engineering enable programmable CD‐ECL systems for bioanalysis, imaging, and future intelligent analytical ...
Yuhan Zhao, Zixuan Chen, Jun‐Jie Zhu
wiley +1 more source
Small, EarlyView.ABSTRACT Bioactive gold plasmonic nanostructures are enabling non‐invasive saliva diagnostics by amplifying weak Raman signals and converting complex biofluid chemistry into information‐rich spectral fingerprints. This Review examines saliva‐based Raman and surface‐enhanced Raman spectroscopy (SERS) integrated with artificial intelligence (AI) from a ...
Ajitesh Dhal +5 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden +10 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness +21 more
wiley +1 more source
Nanoparticle-Assisted Metabolomics
Metabolites, 2018 Understanding and harnessing the interactions between nanoparticles and biological molecules is at the forefront of applications of nanotechnology to modern biology.
Bo Zhang +3 more
doaj +1 more source
Cancer Science, EarlyView.This study demonstrates the selective depletion of tumor‐associated macrophages (TAMs) by targeting CSF1R through near‐infrared photoimmunotherapy (NIR‐PIT). Using a combination of anti‐CSF1R Fab‐IR700 conjugates and localized light irradiation, we achieved tumor suppression and durable antitumor immunity without systemic toxicity.
Kohei Nakajima +6 more
wiley +1 more source
In Vitro Use of Cellular Synthetic Machinery for Biosensing Applications
Frontiers in Pharmacology, 2019 The application of biosensors is expanding in diverse fields due to their high selectivity and sensitivity. Biosensors employ biological components for the recognition of target analytes.
Kyung-Ho Lee, Dong-Myung Kim
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Obesity Reviews, EarlyView.ABSTRACT Maternal overnutrition during pregnancy predisposes children to increased adiposity later in life. This systematic review and meta‐analysis examined how this association persists into adulthood and whether it differs by sex. MEDLINE, EMBASE, Scopus, and CENTRAL were searched for human studies published in English before May 2025.
Szimonetta Eitmann +4 more
wiley +1 more source
Symposium Report: The Waters Bioanalysis World Tour
, 2010 Applied Pharmaceutical Analysis, Baltimore, MD, USA, 19 September 2010 As part of the Waters Corporation Bioanalysis World Tour [101] , an evening symposium was held at the Applied Pharmaceutical Analysis meeting in Baltimore (MD, USA) on 19 September ...
Ryan De Vooght-Johnson
core +1 more source