Results 41 to 50 of about 140,942 (311)
SLAS TechnologyCovalent drug discovery has garnered renewed interest due to its potential to target proteins previously considered ''undruggable.'' Intact protein mass spectrometry (MS) is a critical technique for providing direct evidence of covalent drug ...
Ronghai Cheng +4 more
doaj +1 more source
Evaluating the suitability of plant and crustacean microbiotests for assessing soil toxicity caused by ethylbenzene contamination [PDF]
Archives of Environmental ProtectionPlant and crustacean microbiotests were assessed for their suitability in evaluating soil and groundwater contamination with ethylbenzene (EB) following a railway accident. Bioassays using Lepidium sativum, Sinapis alba, Sorghum saccharatum, Heterocypris
Grzegorz Maciej Kusza +5 more
doaj +1 more source
Activity-based detection of consumption of synthetic cannabinoids in authentic urine samples using a stable cannabinoid reporter system [PDF]
, 2017 Synthetic cannabinoids (SCs) continue to be the largest group of new psychoactive substances (NPS) monitored by the European Monitoring Center of Drugs and Drugs of Abuse (EMCDDA).
Auwärter, Volker +3 more
core +1 more source
Phytotoxic activity and chemical composition of aqueous foliar extracts of Cerrado species
Floresta e Ambiente, 2021 This study aimed to evaluate the phytotoxic activity of aqueous extracts of species from the Cerrado of Mato Grosso on the germination and initial development of lettuce seedlings, as well as to determine the chemical composition of the extracts.
Sharmely Hilares Vargas +6 more
doaj +1 more source
Variation in physiological host range in three strains of two species of the entomopathogenic fungus Beauveria [PDF]
, 2018 Knowledge of the host range of a biocontrol agent (BCA) is fundamental. Host range determines the BCA's economic potential, as well as the possible risk for non-target organisms. Entomopathogenic fungal strains belonging to the genus Beauveria are widely
Besse, Samantha +8 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise +4 more
wiley +1 more source
Disease suppression of potting mixes amended with composted biowaste [PDF]
, 2005 Peat mining destroys valuable nature areas and contributes to the greenhouse effect. This warrants the search for alternatives for peat in potting mixes. Composted biowaste could provide such an alternative.
Blok, Wim J. +4 more
core
Ameliorating Effect of Chloride on Nitrite Toxicity to Freshwater Invertebrates with Different Physiology: a Comparative Study Between Amphipods and Planarians [PDF]
, 2008 High nitrite concentrations in freshwater ecosystems may cause toxicity to aquatic animals. These living organisms can take nitrite up from water through their chloride cells, subsequently suffering oxidation of their respiratory pigments (hemoglobin ...
Alonso, A., Camargo, J.A.
core +2 more sources
Toxicology Research, 2018 Abstract It is time to say goodbye to the standard two-year rodent bioassay. While a few, primarily genotoxic, compounds which are clearly associated with human cancer test positive in the bioassay, there is no science-based, sound foundation for presuming it provides either a valid broad (across different chemicals) capability for ...
openaire +2 more sources