Results 221 to 230 of about 803,201 (379)

Oral Bioavailability of Monoclonal Antibody. [PDF]

open access: yesPharmaceutics
Verma A, Wu S, Shah DK.
europepmc   +1 more source

Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

open access: yesAntioxidants and Redox Signaling, 2013
D. Del Rio   +5 more
semanticscholar   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

open access: yesAdvanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li   +3 more
wiley   +1 more source

DNA‐Inspired Multi‐Functional Double‐Cross‐Linking Self‐Healing Hydrogel Promotes the Healing of Diabetic Wounds

open access: yesAdvanced Science, EarlyView.
A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang   +7 more
wiley   +1 more source

A randomized, double-blind trial on the bioavailability of two CoQ10 formulations

open access: hybrid, 2008
Malkanthi Evans   +3 more
openalex   +1 more source

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