Results 221 to 230 of about 469,546 (342)

Genistein in the Prevention and Treatment of Periodontitis: A Review. [PDF]

Food Sci Nutr
Lu Y, Liang Y, Li Z, Li W, Huang C, Wang Y, Wang G.   +6 more
europepmc   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

Advanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria, Cristina Iglesias, Sascha Jung, Javier Arcos Hodar, Ruben Nogueiras, Antonio del Sol   +5 more
wiley   +1 more source

Plant-Based Diet and Risk of Iron-deficiency Anemia. A Review of the Current Evidence and Implications for Preventive Strategies. [PDF]

Curr Nutr Rep
López-Moreno M, Castillo-García A, Roldán-Ruiz A, Viña I, Bertotti G.   +4 more
europepmc   +1 more source

Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques

Advanced Science, EarlyView.
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu, Junjie Zhang, Yuxiang Zhao, Feixiang Fang, Siyu Zhang, Qiqi An, Jian Zhuang, Feng Xu, Fei Li   +8 more
wiley   +1 more source

Nanomaterial-based encapsulation of biochemicals for targeted sepsis therapy. [PDF]

Mater Today Bio
Li Z, Luo B, Chen Y, Wang L, Liu Y, Jia J, Chen M, Yang S, Shi H, Dai L, Huang L, Wang C, Liu J.   +12 more
europepmc   +1 more source

Nanoscale Metal‐Organic Framework‐Based Self‐Monitoring Oxygen Economizer and ROS Amplifier for Enhanced Radiotherapy‐Radiodynamic Therapy

Advanced Science, EarlyView.
A Fe (III)–Pt (II) porphyrin framework‐based radiosensitizer (FPTM‐LP) is constructed to serve as an oxygen economizer, hypoxia self‐monitoring device, and reactive oxygen species (ROS) amplifier. The glutathione (GSH)/pH‐responsive release of lonidamine achieves oxygen‐economization to combat hypoxia‐induced radioresistance guided by near infrared ...
Shiye Du, Qiang Wen, Ting Han, Jiongyu Ren, Mingyu Wang, Yunpeng Dai, Xiaoguang Ge, Lu Li, Junzhi Liu, Shi Gao   +9 more
wiley   +1 more source

Advancing cancer therapy: Nanomaterial-based encapsulation strategies for enhanced delivery and efficacy of curcumin. [PDF]

Mater Today Bio
Yan Y, Kulsoom, Sun Y, Li Y, Wang Z, Xue L, Wang F.   +6 more
europepmc   +1 more source

Bioavailability of Phosphorus from Defluorinated and Dicalcium Phosphates and Phosphorus Requirement of Calves

, 1987
W.J. Miller, M.W. Neathery, R.P. Gentry, D.M. Blackmon, C.T. Crowe, Glenn O. Ware, A.S. Fielding   +6 more
openalex   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source

High-Fat Meal Increase Blonanserin Bioavailability 5-Fold in Chinese Healthy Subjects. [PDF]

Drug Des Devel Ther
Sun X, Song H, Zhao N, Qiu B, Ding C, Wu H, Bai W.   +6 more
europepmc   +1 more source