Results 71 to 80 of about 432,720 (302)

RSM and AI based machine learning for quality by design development of rivaroxaban push-pull osmotic tablets and its PBPK modeling

Scientific Reports
The study is based on applying Artificial Neural Network (ANN) based machine learning and Response Surface Methodology (RSM) as simultaneous bivariate approaches in developing controlled-release rivaroxaban (RVX) osmotic tablets.
Muhammad Talha Saleem, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Fahad Siddiqui   +3 more
doaj   +1 more source

Responses difference analysis of soil potential nitrification rates to Cu and sulfadiazine

Environmental Pollutants & Bioavailability, 2019
To investigate responses difference of soil potential nitrification rates (PNR) to heavy metals and antibiotics, batch toxicity experiments of Cu and sulfadiazine (SDZ) were conducted in four typical soils which were collected from different locations of
Qiang Liao, Mingzhu Li, Yuanpeng Dong, Yifei Shao, Xijuan Liu, Xinxin Hu, Menghong Li, Aiju Liu   +7 more
doaj   +1 more source

Bioavailability

, 2011
Introduction to the concept of the bioavailability of drugs.

core  

Formulation and processing technologies for enhanced oral bioavailability of poorly water soluble compounds [PDF]

, 2009
textDevelopments in high throughput screening and combinatorial chemistry have contributed to the unprecedented success of the pharmaceutical industry over the last twenty years, leading to a multitude of blockbuster compounds that revolutionized ...
DiNunzio, James Carlo
core  

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source

Effects of root exudates on the sorption of polycyclic aromatic hydrocarbons onto biochar

Environmental Pollutants & Bioavailability, 2019
The effect of oxalic acid on phenanthrene sorption was varied from that on pyrene sorption. 1.0 mg L-1 of oxalic acid inhibited phenanthrene sorption, whereas 20, 50 and 100 mg L-1 of oxalic acid enhanced the sorption.
Xiaona Li, Yang Song, Yongrong Bian, Fang Wang, Chenggang Gu, Xinglun Yang, Xin Jiang   +6 more
doaj   +1 more source

Bioavailability of nutrients for animals : amino acids, minerals, and vitamins /

, 1995
This practical book provides crucial information necessary to formulate diets with appropriate amounts of amino acids, minerals, and vitamins. The factors that influence how well animals obtain these critical nutrients and methods for determining ...
Baker, David H.(David Hiram),1939-2009., Ammerman, Clarence B., Lewis, Austin J.   +2 more
core  

Genetic programming in data mining for drug discovery [PDF]

, 2004
Genetic programming (GP) is used to extract from rat oral bioavailability (OB) measurements simple, interpretable and predictive QSAR models which both generalise to rats and to marketed drugs in humans. Receiver Operating Characteristics (ROC) curves
Barrett, S.J., Langdon, W.B.
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Towards bioavailability-based soil criteria : past, present and future perspectives

, 2015
Bioavailability has been used as a key indicator in chemical risk assessment yet poorly quantified risk factor. Worldwide, the framework used to assess potentially contaminated sites is similar, and the decisions are based on threshold contaminant ...
Harmsen, Joop, Semple, K.T., McGrath, Steve, Harmsen, J., McConnell, S., Pruszinski, Andrew, McGrath, S., Dries, V., Naidu, R., Pruszinski, A., Palanisami, T., McGrath, S. P., Nathanail, Paul, Channey, Rufus, McConnell, Stuart, Dries, Victor, Channey, R., Johnston, Niall, MacMillan, J., Palanisami, Thavamani, Nathanail, P., Macmillan, Janet, Johnston, N., Semple, K. T., Semple, Kirk T., Naidu, Ravi   +25 more
core   +1 more source

Penicillamine Selenotrisulfide as a Selenium-Source in Mice [PDF]

, 2004
In this paper, we compared the bioavailability of penicillamine selenotrisulfide (PenSSeSPen) with the authentic selenium-source compound, selenite. When PenSSeSPen was orally administered to selenium-deficient mice for 7 days, selenium contents of blood,
Ono, Masahiro, Haratake, Mamoru, Nakayama, Morio   +2 more
core   +1 more source