Results 61 to 70 of about 809,060 (344)

Use of isotope dilution method to predict bioavailability of organic pollutants in historically contaminated sediments. [PDF]

open access: yes, 2014
Many cases of severe environmental contamination arise from historical episodes, where recalcitrant contaminants have resided in the environment for a prolonged time, leading to potentially decreased bioavailability.
Bao, Lian-Jun   +4 more
core   +2 more sources

Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols

open access: yesMolecules, 2019
Polyphenols are categorized as plant secondary metabolites, and they have attracted much attention in relation to human health and the prevention of chronic diseases.
K. Kawabata, Yasukiyo Yoshioka, J. Terao
semanticscholar   +1 more source

Role of the Encapsulation in Bioavailability of Phenolic Compounds

open access: yesAntioxidants, 2020
Plant-derived phenolic compounds have multiple positive health effects for humans attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc.
Josip Grgić   +4 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Metabolic profile, bioavailability and toxicokinetics of zearalenone-14-glucoside in rats after oral and intravenous administration by liquid chromatography high-resolution mass spectrometry and tandem mass spectrometry [PDF]

open access: yes, 2019
Zearalenone-14-glucoside (ZEN-14G), a key modified mycotoxin, has attracted a great deal of attention due to the possible conversion to its free form of zearalenone (ZEN) exerting toxicity.
De Boevre, Marthe   +9 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Validating the chronic Pb algae bioavailability model at high pH : single-species evaluation : final report, 12 June 2017 [PDF]

open access: yes, 2017
We investigated toxicity of Pb to Pseudokirchneriella subcapitata using the standard 72h-growth inhibition assays at 2 pH levels (pH 7.2 & pH 8.4) and 2 P (P 10 ug/L & P 100 ug/L) levels, i.e. at 4 treatments in total.
De Schamphelaere, Karel, Nys, Charlotte
core   +1 more source

Application of Co-bioprocessing Techniques (Enzymatic Hydrolysis and Fermantation) for Improving the Nutritional Value of Wheat Bran as Food Functional Ingrediens [PDF]

open access: yes, 2019
Last time the food industry pays the great attention to questions, connected with changing existing technologies for raising the efficacy of the raw materials complex processing and increasing the output of high-quality products and food ingredients with
Buzhylov, M. (Mykola)   +2 more
core   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evaluating the invasive plant, Prosopis juliflora in the two initial growth stages as a potential candidate for heavy metal phytostabilization in metalliferous soil

open access: yesEnvironmental Pollutants & Bioavailability, 2019
Anthropogenic activities leads to increase in toxic metals in the environment. The toxicity of Cd, Cr and Pb to P. juliflora were tested in agar media; Seeds germinated in 25, 50 and 100 mg/L Pb; 5, 10 and 20 mg/ 10 L Cd; and 10 mg/L Cr were mostly ...
Kamal Usman   +2 more
doaj   +1 more source

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