Results 41 to 50 of about 809,060 (344)

Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability

Pharmaceutics, 2021
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse structures out of cells, resulting in poor intestinal permeation and limited bioavailability following oral administration.
Thi-Thao-Linh Nguyen, Van-An Duong, H. Maeng   +2 more
semanticscholar   +1 more source

High removal efficiency of tetracycline (TC) by biochar-supported zerovalent iron composite prepared by co-pyrolysis of hematite and pinewood

Environmental Pollutants & Bioavailability, 2021
There is a need to prepare a high-efficient sorbent to remove the recalcitrant tetracycline (TC) in wastewater. Herein, biochar-supported zerovalent iron (BC/ZVI) was fabricated in nitrogen ambience via one-step co-pyrolysis of hematite and pinewood.
Jun Shi, Xianni Yang, Changai Zhang, Xue Feng, Xiaofei Kong, Xiaozhi Wang, Shengsen Wang   +6 more
doaj   +1 more source

Cyclosporine Absorption Following Orthotopic Liver Transplantation [PDF]

, 1986
Blood concentrations of cyclosporine were determined in adult and pediatric patients following orthotopic liver transplantation to quantitate cyclosporine blood clearance and oral absorption.
Beveridge, Burckart, Burckart, Calne, Calne, Holt, Kahan, Kennedy, Malatack, Miles, Ptachcinski, Ptachcinski, Ptachcinski, Sawchuk, Starzl, Starzl, Starzl, Venkataramanan, Venkataramanan, Venkataramanan, Wood   +20 more
core   +2 more sources

Elemental characterization and risk assessment of indoor aerosols in an electrostatic particle accelerator laboratory

Environmental Pollutants & Bioavailability, 2021
Aerosol samples (PM10 and PM2.5) were collected during the 2018-2019 dry-cold season, inside an electrostatic particle accelerator laboratory at Instituto de Física, Universidad Nacional Autónoma de México, and on the rooftop.
Salvador Reynoso-Cruces, Alfonso Enrique Hernández-López, Javier Miranda, Lourdes Verónica Mejía-Ponce   +3 more
doaj   +1 more source

Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]

, 2015
Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor, Capanoglu, Esra, Grootaert, CharlotteLA23002000065127801001998257F7A30E30-F0ED-11E1-A9DE-61C894A0A6B4, Kamiloglu, SenemUGent0001303221268020017844329746706457840000-0003-3902-4360553D4B12-2C77-11E3-8FFE-9F6610BDE39D, Van Camp, JohnLA238010009006420000-0002-6468-6107F4B233EA-F0ED-11E1-A9DE-61C894A0A6B4   +4 more
core   +3 more sources

Health risk assessment of Ubeji Creek residents’ exposure to BTEX from consumption of locally sourced foods

Environmental Pollutants & Bioavailability, 2021
Ubeji Creek in Niger Delta Region of Nigeria suffers environmental pollution attributable to petroleum exploration. Therefore, this study was undertaken to investigate BTEX (benzene, toluene, ethylbenzene, and xylene) levels in locally sourced staple ...
Gbolahan Iyiola Asejeje, Ayodele Rotimi Ipeaiyeda, Percy Chuks Onianwa   +2 more
doaj   +1 more source

Preparation, Evaluation and Bioavailability Studies of Eudragit Coated PLGA Nanoparticles for Sustained Release of Eluxadoline for the Treatment of Irritable Bowel Syndrome

Frontiers in Pharmacology, 2017
Eluxadoline is a newly approved orally administered drug used for the treatment of Irritable Bowel Syndrome with Diarrhea. It is reported as a poorly water-soluble drug due to which its dissolution rate and oral bioavailability are very poor.
Md. K. Anwer, Ramadan Al-Shdefat, Essam Ezzeldin, Essam Ezzeldin, Saad M. Alshahrani, Abdullah S. Alshetaili, Muzaffar Iqbal, Muzaffar Iqbal   +7 more
doaj   +1 more source

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release [PDF]

, 2011
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug ...
A Al-Omar, A Latrofa, A Miro, A Trapani, A Vyas, AC Jain, AK Upadhyay, AL Nielsen, AS Hoffman, B Haeberlin, B Pose-Vilarnovo, BN Naidu, C Cannavà, C Rodriguez-Tenreiro, C Rupp, C-Y Chen, Catarina Carvalho, Claúdia Conduto, CM Buchanan, CM Fernandes, D Duchêne, D Duchêne, EA Zannou, EY Kim, F Frézard, F Hirayama, G Corti, G Gladys, G Pescitelli, G Trapani, G Wenz, G Zingone, GL Amidon, H Blode, H Hamada, H Matsuda, H Namazi, H Taira, H Yano, HA Archontaki, Helena M. Cabral Marques, HH Sigurdsson, HS Ganapathy, HS Woldum, Inês Sanches, IV Terekhova, J Cheng, J Králová, J Savolainen, J Szejtli, J Szejtli, J Xiong, JJ García-Rodriguez, João Arrais, JP Venter, JR Moyano, JS Smith, JW Wong, K Dua, K Minami, K Motoyama, K Nakanishi, K Okimoto, K Okimoto, K Okimoto, K Terao, K Udo, K Uekama, K Uekama, K Uekama, K-H Frӧmming, KP Chowdary, L Ribeiro, L Szente, L Trichard, M Agüeros, M Agüeros, M Charoenchaitrakool, M Cirri, M Echezarreta-López, M Fukuda, M Jug, M Jug, M Kamada, M Prabaharan, M Roux, M Sauceau, M Temtem, M Türk, M Usuda, M Yoshinari, M-J Zou, ME Zugasti, MT Esclusa-Díaz, MZI Khan, N Mourtzis, N Patel, N Zerrouk, N Zhang, N Özdemir, P Jansook, P Mura, P Mura, P Mura, P Mura, P Mura, Patrícia Pontes, Paulo José Salústio, PJ Salústio, R Cavalli, R Cavalli, R Challa, R Ficarra, R Garg, R Stancanelli, RL Carrier, S Petralito, S Péroche, S Sajeesh, S Sotthivirat, S Sotthivirat, S Szejtli, S Tommasini, S-Y Lee, Shishu, SM Badr-Eldin, T Endo, T Higashi, T Higashi, T Irie, T Loftsson, T Loftsson, T Loftsson, T Vasconcelos, T Yamanoi, V Burckbuchler, V Lemesle-Lamache, VM Rao, W Ling, W Sajomsang, X Lu, X Wen, X-M Liu, Y He, Y Ikeda, Y Ikeda, Y Liu, Y Liu, Y Lu, Y Tozuka, Y Zhou, Y-Z Du, Z Lu, Z Wang   +153 more
core   +1 more source

Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs [PDF]

, 2014
The aim of the study is to increase the bioavailability of itraconazole (ITRA) using nanosized cocrystals prepared via wet milling of ITRA in combination with dicarboxylic acids.
Adriaensens, Peter, Carleer, Robert, De Beer, Thomas, De Smet, Lieselotte, Remon, Jean Paul, Saerens, Lien, Van Bocxlaer, Jan, Vervaet, Chris   +7 more
core   +1 more source

Improved bioavailability

Journal of Advanced Research, 2016
Timolol maleate (TiM), a nonselective β-adrenergic blocker, is a potent highly effective agent for management of hypertension. The drug suffers from extensive first pass effect, resulting in a reduction of oral bioavailability (F%) to 50% and a short ...
Nadia M. Morsi, Ahmed A. Aboelwafa, Marwa H.S. Dawoud   +2 more
doaj   +1 more source