Results 51 to 60 of about 432,720 (302)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Rapid RP-HPLC-UV determination of molnupiravir, nirmatrelvir, and remdesivir alone, in pharmaceutical mixture and plasma

Discover Chemistry
Molnupiravir, nirmatrelvir, and remdesivir are antiviral drugs used in the latest COVID-19 treatment protocols. The proposed method describes a simple, sensitive, and accurate reversed-phase high-performance liquid chromatography (RP-HPLC-UV) for ...
Osama A. Abd-Elmegid, Mounir Zaky, Khaled Elgendy   +2 more
doaj   +1 more source

Evaluating the potential health risk of organochlorine pesticides in selected protein foods from Abeokuta southwestern Nigeria

Environmental Pollutants & Bioavailability, 2020
This study evaluated the potential health risk of OCPs in selected protein foods. A total of 66 food samples were collected from selected areas in Abeokuta, southwestern Nigeria. Food samples were analyzed for OCPs using the standard method.
Adewale Matthew Taiwo, Oluseye Philip Talabi, Abdulahi Akingbolahan Akintola, Ezekiel Tosin Babatunde, Moarufat Olajumoke Olanrewaju, Boluwatife Helen Adegbaju, Samson Lekan Odebo, Aishat Ajoke Bello, Oluwatosin Fatimah Matti, Adeniran Anthony Adesanya, Sakinat Mojisola Ahmad   +10 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Pharmacokinetics of single‐dose rivaroxaban under fed state in obese vs. non‐obese subjects: An open‐label controlled clinical trial (RIVOBESE‐PK)

Clinical and Translational Science
The evidence of rivaroxaban's pharmacokinetics in obese compared with non‐obese populations remains inconclusive. We aimed to compare the pharmacokinetic profile of rivaroxaban between obese and non‐obese populations under fed state. Participants who met
Majdoleen Alalawneh, Ahmed Awaisu, Ibtihal Abdallah, Hazem Elewa, Mohammed Danjuma, Kamal M. Matar, Akram M. ElKashlan, Yasser Elshayep, Fathy Ibrahim, Ousama Rachid   +9 more
doaj   +1 more source

Stream order and connectivity affect phosphorus distribution in plain river network

Environmental Pollutants & Bioavailability, 2020
The order and connectivity of streams influence phosphorus distribution extensively. In this work, the space-and-time variabilities of total phosphorus (TP), particulate phosphorus (PP), total dissolved phosphorus (TDP), dissolved reactive phosphorus ...
Huihua Lyu, Feng Zhou, Na Li
doaj   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Enhanced biodegradation of m-dichlorobenzene by Brevibacillus agri under the coexistence system of Zn(II) and Se(IV)

Environmental Pollutants & Bioavailability, 2020
Appropriate concentration of biological growth additives can improve the treatment effect of organic waste gas by microorganisms. In this work, the growth capability of Brevibacillus agri and the biodegradation efficiency of m-dichlorobenzene were ...
Bairen Yang, Yue Li, Qingqing Shang, Menglei Wu, Qi Zhou, Qi Xu, Cheng Ding   +6 more
doaj   +1 more source

Early clinical development of artemether-lumefantrine dispersible tablet: palatability of three flavours and bioavailability in healthy subjects. [PDF]

, 2010
BACKGROUND\ud \ud Efforts to ease administration and enhance acceptability of the oral anti-malarial artemether-lumefantrine (A-L) crushed tablet to infants and children triggered the development of a novel dispersible tablet of A-L.
Kaiser, Guenther, Abdunoor M Kabanywanyi, Abdulla, Salim, Kabanywanyi Abdunoor M, Salim Abdulla, Reynolds Christine, Nuortti Marja, Gunther Kaiser, Christine Reynolds, Gilbert Lefevre, Nuortti, Marja, Serge Fitoussi, Yeh Ching-Ming, Fitoussi Serge, Romain Sechaud, Marja Nuortti, Kaiser, Günther, Amuri, Baraka, Ubben, David, Yeh, Ching-Ming, Steve Pascoe, David Ubben, Abdulla Salim, Amuri Baraka, Pascoe Steve, Kaiser Günther, Lefèvre, Gilbert, Pascoe, Steve, Ching-Ming Yeh, Kabanywanyi, Abdunoor M, Baraka Amuri, Ubben David, Séchaud Romain, Reynolds, Christine, Séchaud, Romain, Fitoussi, Serge, Lefèvre Gilbert   +36 more
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source