Results 51 to 60 of about 388,078 (310)
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Environmental Pollutants & Bioavailability, 2020 This study investigated the variances in soil microbial community (SMC) structure and metabolic potentials in subtropical mountain forest ecosystem. Soil samples (0–10, 10–30 and 30–60 cm) were collected within 27 plots (20×20 m2) that were randomly ...
Rudong Zhao +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Discover ChemistryMolnupiravir, nirmatrelvir, and remdesivir are antiviral drugs used in the latest COVID-19 treatment protocols. The proposed method describes a simple, sensitive, and accurate reversed-phase high-performance liquid chromatography (RP-HPLC-UV) for ...
Osama A. Abd-Elmegid +2 more
doaj +1 more source
Environmental Pollutants & Bioavailability, 2020 This study evaluated the potential health risk of OCPs in selected protein foods. A total of 66 food samples were collected from selected areas in Abeokuta, southwestern Nigeria. Food samples were analyzed for OCPs using the standard method.
Adewale Matthew Taiwo +10 more
doaj +1 more source
Bioavailability of copper [PDF]
The American Journal of Clinical Nutrition, 1996 Copper intakes of infants and adults are often much lower than current recommendations. Copper status, however, appears adequate in most populations. This suggests that copper requirements may be lower than believed earlier, except those for premature infants, who have high requirements as a result of low prenatal stores.
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng +9 more
wiley +1 more source
Clinical and Translational ScienceThe evidence of rivaroxaban's pharmacokinetics in obese compared with non‐obese populations remains inconclusive. We aimed to compare the pharmacokinetic profile of rivaroxaban between obese and non‐obese populations under fed state. Participants who met
Majdoleen Alalawneh +9 more
doaj +1 more source
Stream order and connectivity affect phosphorus distribution in plain river network
Environmental Pollutants & Bioavailability, 2020 The order and connectivity of streams influence phosphorus distribution extensively. In this work, the space-and-time variabilities of total phosphorus (TP), particulate phosphorus (PP), total dissolved phosphorus (TDP), dissolved reactive phosphorus ...
Huihua Lyu, Feng Zhou, Na Li
doaj +1 more source