Results 121 to 130 of about 171,678 (355)

Prospective derivation of a Living Organoid Biobank of colorectal cancer patients

Cell, 2015
Summary In Rspondin-based three-dimensional cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity.
M. Wetering, Hayley E. Francies, J. Francis, G. Bounova, F. Iorio, A. Pronk, W. V. Houdt, J. Gorp, A. Taylor-Weiner, L. Kester, Anne McLaren-Douglas, J. Blokker, S. Jaksani, S. Bartfeld, Richard Volckman, P. Sluis, Vivian S. W. Li, Sara Seepo, C. Pedamallu, K. Cibulskis, S. Carter, A. McKenna, M. Lawrence, Lee T. Lichtenstein, Chip Stewart, J. Koster, R. Versteeg, A. Oudenaarden, J. Saez-Rodriguez, R. Vries, G. Getz, L. Wessels, M. Stratton, U. McDermott, M. Meyerson, M. Garnett, H. Clevers   +36 more
semanticscholar   +1 more source

The Legislative Initiative for Taiwan Biobank

, 2011
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范建得
core  

The Sciensano biobanks before, during and after the COVID-19 pandemic: challenges and opportunities

, 2023
All Sciensano biobanks were installed conform to the biobank legislation of 2018. This in order to keep preserving and using Sciensano’s existing and future collections of human body material for scientific research, mainly in the domain of infectious ...
A. Vodolazkaia, D. Triest, K. Dierick, K.Espinoza Rimachi, P. Pauss   +4 more
core  

Biobanking across the phenome - at the center of chronic disease research [PDF]

, 2013
Recognized public health relevant risk factors such as obesity, physical inactivity, smoking or air pollution are common to many non-communicable diseases (NCDs). NCDs cluster and co-morbidities increase in parallel to age.
Nicole M Probst-Hensch, Imboden, Medea, Medea Imboden, Probst-Hensch, Nicole M.   +3 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Planning Today for Tomorrow’s Research: Analysis of Factors Influencing Participation in a Pediatric Cancer Research Biorepository

Frontiers in Oncology, 2018
BackgroundBiobanks have become a powerful tool that fosters biomedical research. The success of biobanks depends upon people’s perception and willingness to donate their samples for research.
Rania M. Labib, Omneya Hassanain, Maram Alaa, Safaa Ahmed, Sherif Abou El-Naga   +4 more
doaj   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

I6 passages : sur la reproduction d’une lignée de cellules souches embryonnaires humaines entre Israël et la France

Socio-anthropologie
The first French clinical trial using human embryonic stem cells for regenerative purposes was launched in 2014, using the I6 stem cell line that was imported from Israel.
Noémie Merleau-Ponty, Sigrid Vertommen, Michel Pucéat   +2 more
doaj   +1 more source

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Cell Reports, 2020
Summary: Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease presents with a complex spectrum of genomic aberrations, but the pharmacological consequences of these aberrations are partly unknown.
Patrik Johansson, Cecilia Krona, Soumi Kundu, Milena Doroszko, Sathishkumar Baskaran, Linnéa Schmidt, Claire Vinel, Elin Almstedt, Ramy Elgendy, Ludmila Elfineh, Caroline Gallant, Sara Lundsten, Fernando J. Ferrer Gago, Aleksi Hakkarainen, Petra Sipilä, Maria Häggblad, Ulf Martens, Bo Lundgren, Melanie M. Frigault, David P. Lane, Fredrik J. Swartling, Lene Uhrbom, Marika Nestor, Silvia Marino, Sven Nelander   +24 more
doaj   +1 more source

Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank

BMC Medicine, 2020
Background Understanding of the role of ethnicity and socioeconomic position in the risk of developing SARS-CoV-2 infection is limited. We investigated this in the UK Biobank study. Methods The UK Biobank study recruited 40–70-year-olds in 2006–2010 from
C. Niedzwiedz, C. O’Donnell, B. Jani, E. Demou, F. Ho, C. Celis-Morales, B. Nicholl, F. Mair, P. Welsh, N. Sattar, J. Pell, S. Katikireddi   +11 more
semanticscholar   +1 more source