Results 161 to 170 of about 99,905 (246)

Genetic risk score informed re-evaluation of phenotype quality control to maximise power in epidemiological studies: application to lung function. [PDF]

Int J Popul Data Sci
Chen J, Shrine N, Izquierdo AG, Guyatt A, Williams A, Völzke H, London S, Hall IP, Dudbridge F, SpiroMeta Consortium, CHARGE Consortium, Wain LV, Tobin MD, John C.   +13 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Healthy lifestyle and Alzheimer's disease in individuals with hyperlipidemia: A prospective cohort study. [PDF]

J Prev Alzheimers Dis
Sun D, Yu L, Liao C, Xu Y, Liu W, Wang X.   +5 more
europepmc   +1 more source

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub, Martyn Howard, Brahim Achour, Jill Barber, Naved Alizai, Amin Rostami‐Hodjegan   +5 more
wiley   +1 more source

Migraines and the association of cognitive impairment: a one- and two-sample mendelian randomization analysis. [PDF]

Dialogues Clin Neurosci
Bai CH, Fan HY, Lin HA, Lin SF.
europepmc   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

Epilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud, Christophe Bernard, Birgit Frauscher, Philippa J. Karoly, Vikram R. Rao   +4 more
wiley   +1 more source

Biobanking

, 2015
Kris Dierickx, Kristien Hens
openaire   +1 more source

Unraveling the genetic links between stature and disease in East Asians: A multi-biobank genetic correlation and risk prediction study. [PDF]

PLoS Genet
Lin YJ, Liu TY, Yang JS, Li JP, Chiou JS, Lu HF, Ariyoshi K, Hikino K, Terao C, Chou CH, Liang WM, Chou IC, Lin TH, Liao CC, Huang SM, Tsai FJ.   +15 more
europepmc   +1 more source

Prospective evaluation of a seizure detection wearable device for timely interventions in an epilepsy monitoring unit

Epilepsia, EarlyView.
Abstract Objective This study aimed to evaluate the real‐world performance of a wrist‐worn seizure detection device for timely clinical interventions within an epilepsy monitoring unit (EMU). Methods We conducted a prospective observational study involving patients admitted to the EMU at a tertiary care center.
Amirhossein Jahani, Daniel Alejandro Galindo Lazo, Isabel Sarzo Wabi, Oumayma Gharbi, Manon Robert, Juan Pablo Millan, Gianluca D'onofrio, Alexis Robin, Dang K. Nguyen, Elie Bou Assi   +9 more
wiley   +1 more source

Ethical navigation of biobanking establishment in Ukraine: learning from the experience of developing countries. [PDF]

J Med Ethics
Sulaieva ON, Artamonova O, Dudin O, Semikov R, Urakov D, Zakharash Y, Kacharian A, Strilka V, Mykhalchuk I, Haidamak O, Serdyukova O, Kobyliak N.   +11 more
europepmc   +1 more source