Results 191 to 200 of about 106,316 (267)

Genetics of educational resilience after adverse childhood experiences. [PDF]

EBioMedicine
Yang H, Daníelsdóttir HB, Zeng Y, Hou C, Wang H, Hauksdottir A, Thordardottir EB, Tómasson G, Jakobsdóttir J, Aspelund T, Song J, Fang F, Valdimarsdóttir UA, Song H.   +13 more
europepmc   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Empirically determined baseline masking strategies and other considerations for gene-level burden tests. [PDF]

Nat Genet
Nguyen T, Koesterer R, Haydarlou P, Dornbos P, Yoshiji S, Llamas A, Jang D, Smadbeck P, Moriondo A, Hoang Q, Ruebenacker O, Bezzina CR, Ellinor P, Jurgens SJ, Burtt NP, Flannick J.   +15 more
europepmc   +1 more source

Subtype Differences in Major Adverse Liver Outcomes and Cardiovascular Events and Mortality in Steatotic Liver Disease: A UK Biobank Analysis. [PDF]

Aliment Pharmacol Ther
Miwa T, Díaz LA, Harberts A, Yukawa-Muto Y, Nakamura T, Zhang X, Loomba R, Schnabl B.   +7 more
europepmc   +1 more source

Sex-specific roles of insulin-like growth factor-1, lean mass and fat mass in type 2 diabetes prevention: Mendelian randomization studies in Western and East Asian populations. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Kwok MK, Siu PMF, Luo S, Au Yeung SL, Leung GM, Schooling CM.   +5 more
europepmc   +1 more source

Alzheimer's disease risk prediction from clinical and social determinants of health: a machine learning cohort study in UK Biobank. [PDF]

BMJ Health Care Inform
Hu J, Lu S, Zhang Q, Qian K, Rehman H, Zhu C, Farrell J, Castrillon-Candas JE, Au R, Farrer LA, Qiu WQ, Chen J, Zhang X.   +12 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Association Between Sleep Disorders and Adverse Cardiovascular Outcomes in Patients with Chronic Obstructive Pulmonary Disease: Insights from the UK Biobank. [PDF]

Int J Chron Obstruct Pulmon Dis
An X, Chen Y, Wang Y, Zhu W, Li F, Shen J, Zhang C, Wu Y, Yu R.   +8 more
europepmc   +1 more source

Clinical Validation of Four Point‐of‐Care High‐Risk HPV Assays, Including Two Reduced‐Valency Assays, for Cervical Cancer Screening in Low‐Resource Settings

International Journal of Cancer, EarlyView.
High‐risk human papillomavirus (hrHPV) testing improves cervical cancer screening by facilitating earlier detection and prevention. In low‐resource settings, however, cost and increased referrals limit its use. At the same time, many new and more affordable assays lack validation.
Neerja Bhatla, MaryLuz Rol, Seema Singhal, Showket Hussain, Anushree Patil, Pranay Tanwar, Shalini Singh, Vikrant M. Bhor, Kiran Munne, Richa Vashishtha, Shachi Vashist, Eric Lucas, Richard Muwonge, Arianis Tatiana Ramírez, Anju Singh, Vikas Khan, Jyoti Rani, Nasera Firdausi, Sandeep Sisodiya, Rutuja Wakchaure, María Alejandra Picconi, Alejandro Calderón, Margo Bell, Annemie De Smet, Alex Vorsters, Gary M. Clifford, Madhavi Chandra, Jitendra Kumar, Partha Basu   +28 more
wiley   +1 more source

Genetic analysis of TGFBI variants in the Taiwanese population: from granular corneal dystrophy type 1 to a broader phenotypic spectrum. [PDF]

Am J Transl Res
Han YS, Wu YF, Chen YL, Hung DK.
europepmc   +1 more source