Results 111 to 120 of about 27,233 (308)

Does ADR’s “Access to Justice” Come at the Expense of Meaningful Consent? [PDF]

, 2018
Over the last forty years, ADR processes, in particular mediation and arbitration, have been advanced as vehicles to secure access to justice for individual litigants and to improve efficiency in overburdened court systems.
Nolan-Haley, Jacqueline
core   +1 more source

Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative [PDF]

, 2017
Innovative research in childhood rheumatic diseases mandates international collaborations. However, researchers struggle with significant regulatory heterogeneity; an enabling European Union (EU)-wide framework is missing.
Anton, Jordi, Avcin, Tadej, Benseler, Susanne M, Beresford, Michael W, Constantin, Tamas, Eikelberg, Andreas, Foster, Helen E, Hansmann, Sandra, Haug, Iris, Hens, Kristien, Horneff, Gerd, Jaegle, Christine, Kone-Paut, Isabelle, Kuemmerle-Deschner, Jasmin B, Martini, Alberto, Ozen, Seza, Prakken, Berent J, Ravelli, Angelo, Ruperto, Nicolino, Schuller, Sabrina, Shaw, David, Sikken, Marijn, Uziel, Yosef, Vastert, Sebastiaan J, Wouters, Carine, Wulffraat, Nico M   +25 more
core   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

Advancements in Umbilical Cord Biobanking: A Comprehensive Review of Current Trends and Future Prospects

Stem Cells and Cloning: Advances and Applications
Sahar AlOraibi, Sebastien Taurin, Sfoug Alshammary Molecular Medicine Department, Princess Al Jawhara Center for Molecular Medicine, Genetics, and Hereditary Diseases, College of Medicine and Health Sciences, Arabian Gulf University, Manama ...
AlOraibi S, Taurin S, Alshammary S
doaj  

Interview with the Coordinator Prof. Giuseppe Di Giovanni, University of Malta, Department of Physiology and Biochemistry [PDF]

, 2015
Interview with the Coordinator of the Malta Neuroscience Network Programme, Prof. Giuseppe Di Giovanni regarding the Malta Neuroscience Net- work. "With the creation of the Malta Neuroscience Network, we will be keeping up with the most important ...
Di Giovanni, Giuseppe
core  

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Risk mapping for better governance in biobanking: the case of biobank.cy

Frontiers in Genetics
Introduction: Risk governance is central for the successful and ethical operation of biobanks and the continued social license for being custodians of samples and data. Risks in biobanking are often framed as risks for participants, whereas the biobank’s
Kaya Akyüz, Melanie Goisauf, Gillian M. Martin, Michaela Th. Mayrhofer, Stella Antoniou, Georgia Charalambidou, Constantinos Deltas, Constantinos Deltas, Apostolos Malatras, Gregory Papagregoriou, Charalambos Stefanou, Mariel Voutounou   +11 more
doaj   +1 more source

Understanding Ethical, Legal and Societal Issues (ELSIs) in Human Biobanking and Genomics for Research and Healthcare in Zimbabwe: The Genomics Inheritance Law Ethics and Society (GILES) initiative [version 2; peer review: 2 approved]

AAS Open Research, 2019
Biobanks and human genomics applications are key for understanding health, disease and heredity in Africa and globally. Growing interest in these technologies calls for strengthening relevant legal, ethical and policy systems to address knowledge ...
Alice Matimba, Andrew Chimatira, Oppah Kuguyo, James January, Zivayi Mupambireyi, Bazondlile Marimbe-Dube, Vasco Chikwasha, Zibusiso Nyati-Jokomo, Shamiso Muteti, Pedzisayi Mangezvo, Abigail Kangwende, Alfred Chingono, Midion Chidzonga, Jonathan Gandari, James Hakim, Kusum Nathoo, Christopher Samkange, Walter Mangezi, Sandra Lee, Lovemore Gwanzura, Mildred Cho, Paul Ndebele   +21 more
doaj   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Consent for the use of human biological samples for biomedical research: a mixed methods study exploring the UK public’s preferences [PDF]

, 2013
OBJECTIVE: A mixed-methods study exploring the UK general public's views towards consent for the use of biosamples for biomedical research.<p></p> SETTING: Cross-sectional population-based focus groups followed by an online survey.<p>&
Clotworthy, M, Corfield, J, Hilton, S, Lewis, C, Magee, C, Robertson, MJ, Stubbins, LJ   +6 more
core   +1 more source