Results 91 to 100 of about 27,233 (308)

Biobanking—Budgets and the Role of Pathology Biobanks in Precision Medicine

Academic Pathology, 2017
Biobanks have become an important component of the routine practice of pathology. At the 2016 meeting of the Association of Pathology Chairs, a series of presentations covered several important aspects of biobanking.
Chris Andry MPhil, PhD, Elizabeth Duffy MA, Christopher A. Moskaluk MD, PhD, Shannon McCall MD, Michael H. A. Roehrl MD, PhD, Daniel Remick MD   +5 more
doaj   +1 more source

The UK DNA banking network: a “fair access” biobank [PDF]

, 2009
The UK DNA Banking Network (UDBN) is a secondary biobank: it aggregates and manages resources (samples and data) originated by others. The network comprises, on the one hand, investigator groups led by clinicians each with a distinct disease specialism ...
Martin Yuille, Katherine Dixon, Andrew Platt, Simon Pullum, David Lewis, Alistair Hall, William Ollier, G Davey Smith, DF Easton, W Ollier, The GAIN Collaborative Research Group, Wellcome Trust Case Control Consortium, M Yuille   +12 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Engaging Maori in Biobanking and Genetic Research: Legal, Ethical, and Policy Challenges

International Indigenous Policy Journal, 2015
Publically funded biobanking initiatives and genetic research should contribute towards reducing inequalities in health by reducing the prevalence and burden of disease.
Angela Beaton, Barry Smith, Valmaine Toki, Kim Southey, Maui Hudson   +4 more
doaj  

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression [PDF]

, 2019
Many workers are daily exposed to occupational agents like gases/fumes, mineral dust or biological dust, which could induce adverse health effects. Epigenetic mechanisms, such as DNA methylation, have been suggested to play a role.
't Hoen, Peter-Bram, Amin, Najaf, Arindrarto, Wibowo, Beekman, Marian, Boezen, H Marike, Bonder, Marc Jan, Boomsma,, Dorret I, Bot, Jan, Brusselle, Guy, de Jong, Kim, de Vries, Maaike, Deelen, Joris, Deelen, Patrick, Franke, Lude, Heijmans, Bastiaan T, Hoen, Peter ACT, Hofman, Bert A, Hottenga, Jouke J, Isaacs, Aaron, Jansen, Rick, Jhamai, P Mila, Kielbasa, Szymon M, Kromhout, Hans, La Bastide-van Gemert, Sacha, Lahousse, Lies, Lakenberg, Nico, Luijk, Rene, Mei, Hailiang, Moed, Matthijs, Nedeljkovic, Ivana, Nooren, Irene, Pool, Rene, Postma, Dirkje S, Schalkwijk, Casper G, Slagboom, P Eline, Stehouwer, Coen DA, Suchiman, H Eka D, Swertz, Morris A, Terzikhan, Natalie, Tigchelaar, Ettje E, Uitterlinden, Andre G, van den Berg, Leonard H, van Der Breggen, Ruud, van Der Kallen, Carla JH, van Der Plaat, Diana, van Diemen, Cleo C, van Dijk, Freerk, van Dongen, Jenny, van Duijn, Cornelia M, van Galen, Michiel, van Greevenbroek, Marleen MJ, van Heemst, Diana, van Iterson, Maarten, van Meurs, Joyce, van Rooij, Jeroen, van Zwet, Erik W, Vant Hof, Peter, Veldink, Jan H, Verbiest, Michael, Verkerk, Marijn, Vermaat, Martijn, Vermeulen, Roel CH, Vonk, Judith M, Wijmenga, Cisca, Zhernakova, Dasha V, Zhernakova, Sasha   +65 more
core   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

JMIR Bioinformatics and Biotechnology
BackgroundBiobank privacy policies strip patient identifiers from donated specimens, undermining transparency, utility, and value for patients, scientists, and society. We are advancing decentralized biobanking apps that reconnect
William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross   +7 more
doaj   +1 more source

Pilot-testing a Cancer 101 Education Curriculum with the Fairbanks Native Association’s Women & Children’s Center for Inner Healing [PDF]

, 2014
Cancer is the leading cause of death among Alaska Native people Nevertheless, due to improved detection awareness about cancer prevention, early screening and advances in treatment survival rates are ...
Billings, James, Lopez, Ellen D. S., Villalobos, Ciara, Williams, Freda M.   +3 more
core  

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source