Results 61 to 70 of about 61,606 (334)

Harmonizing the COVID-19 sample biobanks: Barriers and opportunities for standards, best practices and networks

Biosafety and Health, 2022
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the practice of infectious diseases biobanking, as well as existing challenges and opportunities.
Balwir Matharoo-Ball, Mbayame Diop, Zisis Kozlakidis   +2 more
doaj   +1 more source

Human iPSC Reprogramming Success: The Impact of Approaches and Source Materials

Stem Cells International
Since their discovery, human induced pluripotent stem cells (hiPSCs) have been instrumental in biomedical research, particularly in the fields of disease modelling, drug screening and regenerative therapies.
Tatyana Pozner, Christine Grandizio, Matthew W. Mitchell, Nahid Turan, Laura Scheinfeldt   +4 more
doaj   +1 more source

Constructing effective ethical frameworks for biobanking [PDF]

, 2010
This paper is about the actual and potential development of an ethics that is appropriate to the practices and institutions of biobanking, the question being how best to develop a framework within which the relevant ethical questions are first identified
Cordell, Sean, Widdows, Heather
core  

Enhancing reuse of data and biological material in medical research : from FAIR to FAIR-Health [PDF]

, 2018
The known challenge of underutilization of data and biological material from biorepositories as potential resources formedical research has been the focus of discussion for over a decade. Recently developed guidelines for improved data availability and
Casati, Sara, Dagher, Georges, Gabriele, Anton, Holub, Petr, Kohlmayer, Florian, Koumakis, Lefteris, Kozera, Łukasz, Lavitrano, Marialuisa, Litton, Jan-Eric, Martin, Gillian M., Mendy, Maimuna, Ommen, GertJan B. van, Prasser, Fabian, Schlunder, Irene, Sezerman, Osman Ugur, Strapagiel, Dominik, Th. Mayrhofer, Michaela, Valik, Dalibor, Wutte, Andrea, Zanetti, Gianluigi, Zatloukal, Kurt   +20 more
core   +1 more source

The ethics of data sharing and biobanking in health research

Wellcome Open Research, 2020
The importance of data sharing and biobanking are increasingly being recognised in global health research. Such practices are perceived to have the potential to promote science by maximising the utility of data and samples.
S. Bull, N. Bhagwandin
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The landscape of biobanks in Poland—characteristics of Polish biobanking units at the beginning of BBMRI.pl organization

Journal of Translational Medicine, 2021
Background Biobanking is an area of scientific activity that is growing in strength and importance. The variety of collections combining biological samples and medical scientific information makes biobanking an indispensable tool in the development of ...
Anna Chróścicka, Angelika Paluch, Łukasz Kozera, Małgorzata Lewandowska-Szumieł   +3 more
doaj   +1 more source

Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).

Clinical Chemistry, 2018
BACKGROUND The metabolome of any given biological system contains a diverse range of low molecular weight molecules (metabolites), whose abundances can be affected by the timing and method of sample collection, storage, and handling.
J. Kirwan, L. Brennan, D. Broadhurst, O. Fiehn, M. Cascante, W. Dunn, Michael A. Schmidt, V. Velagapudi   +7 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Fecal microbiota transplants: Emerging social representations in the English-language print media [PDF]

, 2019
open access articleThis study investigates how English-language news sources have represented fecal microbiota transplants (FMT). FMT involves transferring stool from a healthy donor to a recipient with a dysfunctional intestinal flora in order to ...
Jaspal, Rusi, McLeod, Carmen, Nerlich, Brigitte   +2 more
core   +4 more sources