Results 91 to 100 of about 23,670 (299)

Data protection in biobanks--a European challenge for the long-term sustainability of biobanking.

open access: yes, 2009
The final decoding of the human genome has marked the beginning of a new era of biomedical research and both the European Commission (EC) and the Member States try to facilitate this new research direction.
Paci, Daniele   +2 more
core  

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

open access: yesArthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler   +20 more
wiley   +1 more source

Biobanks and Informed Consent

open access: yesVoices in Bioethics, 2014
Biobanks have added complexity to the idea of informed consent, which is an important ethical component in research involving human subjects. The idea behind informed consent is that each potential participant needs to voluntarily determine whether or ...
Gabriella Foe
doaj   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran   +15 more
wiley   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina   +5 more
wiley   +1 more source

HUMAN GENETIC BIOBANKS IN ASIA: POLITICS OF TRUST AND SCIENTIFIC ADVANCEMENT

open access: yes, 2009
List of illustrations -- List of contributors -- Acknowledgements -- Introduction -- 1. Human genetic biobanking in Asia: issues of trust, wealth and ambition / Margaret Sleeboom-Faulkner -- Pt. I: Biobanking in welfare societies -- 2. Public trust,
Sleeboom-Faulkner, Margaret, ed.
core  

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

open access: yesAdvanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun   +27 more
wiley   +1 more source

Biobanks and Ethical Concerns [PDF]

open access: yes, 2017
This review critically discussed three ethical concerns of biobanks: consent, altruism, and benefit. Informed consent, altruism, and benefit are issues that must be address in an ethical manner in relation to the operation of biobanks.
Alanazi, Mohammed, Alanazi, Mansour
core   +1 more source

The Significance of Biobanking in the Sustainability of Biomedical Research: A Review

open access: yesIranian Biomedical Journal, 2020
Biobank, defined as a functional unit for facilitating and improving research by storing biospecimen and their accompanying data, is a key resource for advancement in life science.
Mahshid Zohouri, Abbas Ghaderi
doaj  

Biobanks: oversight offers protection.

open access: yes, 2009
letter and replyhttp://dx.doi.org/10.1126/science ...
Fortier, Isabel   +6 more
core   +1 more source

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