Results 81 to 90 of about 32,321 (308)

Biobank Digitalization: From Data Acquisition to Efficient Use

open access: yesBiology
Biobanks are involved in a broad range of studies, including both basic and clinical research, so their functions and roles are evolving. Digital biobanks have emerged due to digitalization in this field; however, it also entails an increasing number of ...
Anastasiia S. Bukreeva   +7 more
doaj   +1 more source

Penser le corps-marchandise avec Alfred Sohn-Rethel

open access: yesRecherches Germaniques, 2020
This article analyzes the commodification of the human body with the help of Alfred Sohn-Rethel’s work, which clarifies two distinct processes. On the one hand, it shows that monetization is only possible by reducing reality to a quantity.
Fabrice Colomb
doaj   +1 more source

Systematic review of birth cohort studies in South East Asia and Eastern Mediterranean regions [PDF]

open access: yes, 2011
Few longitudinal studies of children have taken place in the developing world, despite child mortality being concentrated there. This review summarises the methodologies and main outcomes of longitudinal studies of pre-school children (0 to 59 months) in
Campbell, Harry, McKinnon, Rachel
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

La marchandisation du corps à l’épreuve des biobanques

open access: yesLa Nouvelle Revue du Travail, 2019
The article views biobanking in France as one way of apprehending the commodification of the human body. It applies a Marxist understanding of commodities to analyse what happens to biological samples once they have been treated by biobanks.
Fabrice Colomb
doaj   +1 more source

Biobank Economics and the “Commercialization Problem” [PDF]

open access: yes, 2013
The economic aspects of biobanking are intertwined with the social and scientific aspects. We describe two problems that structure the discussion about the economics of biobanking and which illustrate this intertwining.
Dallaire-Fortier, Clara   +2 more
core   +3 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Exosomal delivery of CRISPR/Cas9 complexes for targeted editing of KRAS^G12D in pancreatic cancer: prerequisites for clinical surgical application

open access: yesУкраїнський журнал клінічної хірургії
Objective. To evaluate exosomes obtained from patients with ductal adenocarcinoma of the pancreas as carriers of CRISPR/Cas9 complexes for targeted editing of KRAS^G12D in pancreatic cancer and to test their stability, editing efficiency, and ...
S. M. Gramatyuk   +5 more
doaj   +1 more source

Biobank networking and globalisation: perspectives and practices of Australian biobanks

open access: yesAustralian Health Review, 2020
Objective This study examined the practices and attitudes of Australian biobanks regarding access to samples and data, as well as local and global networking with other biobanks. Methods This was a mixed-methods study, including an ...
Edwina Light   +8 more
openaire   +5 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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