Results 191 to 200 of about 31,338 (290)

Before Symptoms Begin: Immune Activation in Preclinical ALS

Annals of Neurology, EarlyView.
Adriano Chiò, Andrea Calvo
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Systematic genetic investigation on relative macronutrient intake, circulating metabolic biomarkers and the risk of autoimmune diseases. [PDF]

NPJ Sci Food
Zheng S, Na G, Liang K, Meng D, Shan Y, Chen D.   +5 more
europepmc   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

Epilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud, Christophe Bernard, Birgit Frauscher, Philippa J. Karoly, Vikram R. Rao   +4 more
wiley   +1 more source

Maternal Determinants of Human Milk Leptin and Their Associations with Neonatal Growth Parameters. [PDF]

Nutrients
Garro-Aguilar Y, Astigarraga E, Barreda-Gómez G, Martinez O, Simón E.   +4 more
europepmc   +1 more source

Novel polygenic risk score associates with diverticulitis in a multi-institutional, ancestrally diverse cohort. [PDF]

Sci Rep
Neylan CJ, Ueland T, Abramowitz SA, DePaolo JS, Tsao NL, Roberson JL, Hawkins AT, Carey DJ, Smelser DT, Levin MG, Hoffman RL, Damrauer SM, Maguire LH.   +12 more
europepmc   +1 more source

Prospective evaluation of a seizure detection wearable device for timely interventions in an epilepsy monitoring unit

Epilepsia, EarlyView.
Abstract Objective This study aimed to evaluate the real‐world performance of a wrist‐worn seizure detection device for timely clinical interventions within an epilepsy monitoring unit (EMU). Methods We conducted a prospective observational study involving patients admitted to the EMU at a tertiary care center.
Amirhossein Jahani, Daniel Alejandro Galindo Lazo, Isabel Sarzo Wabi, Oumayma Gharbi, Manon Robert, Juan Pablo Millan, Gianluca D'onofrio, Alexis Robin, Dang K. Nguyen, Elie Bou Assi   +9 more
wiley   +1 more source

Time to use large-scale biobank databases in health policy and public health research. [PDF]

Health Aff Sch
Pagán JA, Wang VH, Sur H.
europepmc   +1 more source

A novel PTEN variant causing hemimegalencephaly and focal nodular heterotopias in the developing human brain

Epilepsia, EarlyView.
Abstract Brain development and subsequent brain function are highly sensitive to genetic mutations, which can result in severe neurodevelopmental malformations. Alterations in PTEN signaling cause a spectrum of developmental malformations and neurological diseases including epilepsy.
Franziska Fazekas, Amit Haboosheh, Bernhard Hennebichler, Thomas Roetzer‐Pejrimovsky, Julia Binder, Theresa Reischer, Mateja Pfeifer, Anke Scharrer, Christof Worda, Tina Linder, Alex Farr, Romana Höftberger, Ellen Gelpi, Christian Mitter, Gregor Kasprian, Christine Haberler, Nicole Amberg   +16 more
wiley   +1 more source

Lung cancer biobanking in Australia: challenges and future directions. [PDF]

Med J Aust
Yeo S, Wong SQ, Atashrazm F, Behren A, Papenfuss AT, Vukelic N, Briggs L, Poh AR, Steinfort D, Smallwood N, Sutherland K, Naranbhai V, Parakh S, Leong T.   +13 more
europepmc   +1 more source