Results 191 to 200 of about 31,631 (243)

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Unveiling Hepatic Protein Alterations in Neonatal and Infant Biliary Atresia

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pediatric populations differ from adults in drug elimination capacity. While current scaling methods account for enzyme and transporter maturation, they overlook comorbidities, such as biliary atresia (BA), a liver disease appearing within the first 2–8 weeks of life that can progress to cirrhosis.
Zubida M. Al‐Majdoub   +5 more
wiley   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

open access: yesEpilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud   +4 more
wiley   +1 more source

Prospective evaluation of a seizure detection wearable device for timely interventions in an epilepsy monitoring unit

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to evaluate the real‐world performance of a wrist‐worn seizure detection device for timely clinical interventions within an epilepsy monitoring unit (EMU). Methods We conducted a prospective observational study involving patients admitted to the EMU at a tertiary care center.
Amirhossein Jahani   +9 more
wiley   +1 more source

Genetic, lifestyle and environmental influences on health: a Finnish biobank recall study protocol (BioRecall). [PDF]

open access: yesBMJ Open
Sillanpää E   +11 more
europepmc   +1 more source

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