Results 31 to 40 of about 31,631 (243)

Integrating population-based biobanks: Catalyst for advances in precision health

open access: yesComputational and Structural Biotechnology Journal
Precision health extends beyond the scope of precision medicine and involves a broader range of activities, including the prediction, prevention, treatment, and management of diseases.
Jui-Chu Lin   +3 more
doaj   +1 more source

Population's perspectives toward biobanks in scientific research: a study from Jordan. [PDF]

open access: yes, 2019
BackgroundBiobanks (biorepositories) were established to compile collected bio-specimens for future research and usage. The collection/storage of bio-specimens triggers several social, legal, and ethical implications where public attitudes can represent ...
Al-Delaimy, Wael   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Marine Biotechnology: A New Vision and Strategy for Europe [PDF]

open access: yes, 2013
Marine Board-ESF The Marine Board provides a pan-European platform for its member organisations to develop common priorities, to advance marine research, and to bridge the gap between science and policy in order to meet future marine science challenges ...
Boyen, C.   +10 more
core   +6 more sources

Clinical trials and the importance of biobanks in rare diseases [PDF]

open access: yesScripta Medica, 2018
Rare diseases ('orphan diseases') (RDs) count for 5000-8000 diseases with low prevalence and most commonly of genetic origin. Although most of rare diseases are manifested in early childhood, many are diagnosed in adults, even in elderly.
Nežić Lana   +3 more
doaj  

The Public’s Awareness of and Attitude Toward Research Biobanks – A Regional German Survey

open access: yesFrontiers in Genetics, 2018
Background: Biobanks have become an increasingly important means of biomedical research and innovation. However, they entail a variety of ethical, social and legal challenges, which need to be publicly discussed and managed collectively.
Sabine Bossert   +2 more
doaj   +1 more source

From pharmacogenetics to pharmaco-omics: Milestones and future directions

open access: yesHGG Advances, 2022
The origins of pharmacogenetics date back to the 1950s, when it was established that inter-individual differences in drug response are partially determined by genetic factors.
Chiara Auwerx   +3 more
doaj   +1 more source

Constructing effective ethical frameworks for biobanking [PDF]

open access: yes, 2010
This paper is about the actual and potential development of an ethics that is appropriate to the practices and institutions of biobanking, the question being how best to develop a framework within which the relevant ethical questions are first identified
Cordell, Sean, Widdows, Heather
core  

an explorative survey [PDF]

open access: yes, 2016
Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility.
Anagnostou, Paolo   +6 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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