Results 51 to 60 of about 32,321 (308)
The UCLA ATLAS Community Health Initiative: Promoting precision health research in a diverse biobank
Cell Genomics, 2023 Summary: The UCLA ATLAS Community Health Initiative (ATLAS) has an initial target to recruit 150,000 participants from across the UCLA Health system with the goal of creating a genomic database to accelerate precision medicine efforts in California. This
Ruth Johnson +7 more
doaj +1 more source
Constructing effective ethical frameworks for biobanking [PDF]
, 2010 This paper is about the actual and potential development of an ethics that is appropriate to the practices and institutions of biobanking, the question being how best to develop a framework within which the relevant ethical questions are first identified
Cordell, Sean, Widdows, Heather
core
British Journal of Cancer, 2008 Biobank research has been the focus of great interest of scholars and regulatory bodies who have addressed different ethical issues. On the basis of a review of the literature it may be concluded that, regarding some major themes in this discussion, a consensus seems to emerge on the international scene after the regular exchange of arguments in ...
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Public awareness, attitudes, and motivation toward biobanks: a survey of China
BMC Medical EthicsBackground Biobanks are vital for advancing medical research, and public participation is a crucial determinant of their success. This study uses a survey to assess the awareness, attitudes, and motivation of the public in China with regard to ...
Mingtao Huang +6 more
doaj +1 more source
The Public’s Awareness of and Attitude Toward Research Biobanks – A Regional German Survey
Frontiers in Genetics, 2018 Background: Biobanks have become an increasingly important means of biomedical research and innovation. However, they entail a variety of ethical, social and legal challenges, which need to be publicly discussed and managed collectively.
Sabine Bossert +2 more
doaj +1 more source
Lung cancer organoids: models for preclinical research and precision medicine
Frontiers in Oncology, 2023 Lung cancer is a malignancy with high incidence and mortality rates globally, and it has a 5-year survival rate of only 10%–20%. The significant heterogeneity in clinical presentation, histological features, multi-omics findings, and drug sensitivity ...
Yajing Liu +4 more
doaj +1 more source
Bioethics, Complementarity, and Corporate Criminal Liability [PDF]
, 2017 This article provides a brief introduction to some contemporary challenges found in the intersection of bioethics and international criminal law involving genetic privacy, organ trafficking, genetic engineering, and cloning.
Long, Ryan
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The case for launch of an international DNA-based birth cohort study [PDF]
, 2011 The global health agenda beyond 2015 will inevitably need to broaden its focus from mortality reduction to the social determinants of deaths, growing inequities among children and mothers, and ensuring the sustainability of the progress made against the ...
Aulchenko, Yurii +19 more
core +1 more source