Results 31 to 40 of about 995 (116)
From pharmacogenetics to pharmaco-omics: Milestones and future directions
HGG Advances, 2022 The origins of pharmacogenetics date back to the 1950s, when it was established that inter-individual differences in drug response are partially determined by genetic factors.
Chiara Auwerx +3 more
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Access to Biobanks: Harmonization Across Biobank Initiatives [PDF]
Biopreservation and Biobanking, 2014 The current study investigates whether access arrangements relevant for biobanking contain clear information on key access conditions. It furthermore assesses the extent to which these access conditions are harmonized across biobank initiatives.A comparative analysis was conducted of access arrangements developed by 26 organizations, 36 biobank ...
Michiel, Verlinden +3 more
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Integrating population-based biobanks: Catalyst for advances in precision health
Computational and Structural Biotechnology JournalPrecision health extends beyond the scope of precision medicine and involves a broader range of activities, including the prediction, prevention, treatment, and management of diseases.
Jui-Chu Lin +3 more
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Clinical trials and the importance of biobanks in rare diseases [PDF]
Scripta Medica, 2018 Rare diseases ('orphan diseases') (RDs) count for 5000-8000 diseases with low prevalence and most commonly of genetic origin. Although most of rare diseases are manifested in early childhood, many are diagnosed in adults, even in elderly.
Nežić Lana +3 more
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The UCLA ATLAS Community Health Initiative: Promoting precision health research in a diverse biobank
Cell Genomics, 2023 Summary: The UCLA ATLAS Community Health Initiative (ATLAS) has an initial target to recruit 150,000 participants from across the UCLA Health system with the goal of creating a genomic database to accelerate precision medicine efforts in California. This
Ruth Johnson +7 more
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Lung cancer organoids: models for preclinical research and precision medicine
Frontiers in Oncology, 2023 Lung cancer is a malignancy with high incidence and mortality rates globally, and it has a 5-year survival rate of only 10%–20%. The significant heterogeneity in clinical presentation, histological features, multi-omics findings, and drug sensitivity ...
Yajing Liu +4 more
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British Journal of Cancer, 2008 Biobank research has been the focus of great interest of scholars and regulatory bodies who have addressed different ethical issues. On the basis of a review of the literature it may be concluded that, regarding some major themes in this discussion, a consensus seems to emerge on the international scene after the regular exchange of arguments in ...
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Public awareness, attitudes, and motivation toward biobanks: a survey of China
BMC Medical EthicsBackground Biobanks are vital for advancing medical research, and public participation is a crucial determinant of their success. This study uses a survey to assess the awareness, attitudes, and motivation of the public in China with regard to ...
Mingtao Huang +6 more
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The Public’s Awareness of and Attitude Toward Research Biobanks – A Regional German Survey
Frontiers in Genetics, 2018 Background: Biobanks have become an increasingly important means of biomedical research and innovation. However, they entail a variety of ethical, social and legal challenges, which need to be publicly discussed and managed collectively.
Sabine Bossert +2 more
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Biobank@VITO: Biobanking the General Population in Flanders
Frontiers in Medicine, 2020 During the last 15 years, VITO has established an infrastructure for biobanking a collection of biological samples from the general population in Flanders (Belgium). This biobank was set up to contribute to future, yet unspecified, research questions in the field of environment and health.
Rosette Van Den Heuvel +5 more
openaire +3 more sources