Results 91 to 100 of about 32,636 (240)

Induction and Enhancement of Bacteriocin Production (Review)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley   +1 more source

Scale‐Down Platforms for Process‐Oriented Enzyme Screening Using Microfluidics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Enzyme screening platforms are typically evaluated based on their throughput and analytical performance rather than their ability to mimic the conditions encountered at large scale. In bioreactors, enzymes experience gradients in substrate concentration, oxygen availability, pH, temperature, and interfacial exposure, caused by imperfect mixing
Maria I. Rodriguez‐Torres, Elif Erdem, Junhyeong Wang, Ulrich Krühne, Michael Daniele, John M. Woodley   +5 more
wiley   +1 more source

The 11th International Congress on Biocatalysis (biocat2024), Hamburg, Germany, 25–29 August 2024

The “11th International Congress on Biocatalysis (biocat2024)” was part of a biennial series that unites the fields of biology and chemistry, attracting researchers from the life sciences, engineering, and computer science. This international
Daniel Ohde, Anna-Lena Heins, Franziska Rohweder, Paul Bubenheim, Ana Malvis Romero, Johannes Gescher, Andreas Liese, Victoria Bueschler, Barbara Klippel   +8 more
core   +1 more source

Immobilization of Alginate Microbeads With Whole‐Cells Expressing Nitrilase for Continuous Nicotinic Acid Production in Chip Millireactor

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The biocatalytic production of nicotinic acid using nitrilases has emerged as a promising alternative to conventional chemical synthesis, offering improved selectivity and environmental sustainability. In this study, we developed a continuous‐flow millireactor system employing Escherichia coli cells expressing a nitrilase from Paraburkholderia
Jonathan Bassut, Emina Mehić, Luana Cuvillier, Carine Vergne‐Vaxelaire, Jean‐Louis Petit, Maïté Michaud, Zoé Anxionnaz‐Minvielle, Anne Zaparucha, Guillaume Nonglaton   +8 more
wiley   +1 more source

Biocatalysis - New tasks, new approaches

, 2010
Flaschel E. Biocatalysis - New tasks, new approaches. CHEMIE INGENIEUR TECHNIK.
Flaschel, Erwin, Erwin Flaschel
core   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Online monitoring of phytate content in plant residuals during wet-treatment

Scientific Reports
The occurrence of organically bound phosphorus (P) as phytate in plant-based feeding material is a challenge for livestock farming due to limited utilization during the digestion by the animal.
Niklas Widderich, Paul Bubenheim, Andreas Liese   +2 more
doaj   +1 more source

Scalable catalyst production process for oleate hydratase whole‐cell biocatalysis

Biotechnology Progress, EarlyView.
This study establishes a scalable lactose‐induced fed‐batch fermentation for an Escherichia coli whole‐cell biocatalyst containing an oleate hydratase. Operation at a higher growth rate markedly increased biomass yields while maintaining catalyst activity and was demonstrated at 150 L scale.
Rebekka Horstmann, Mario Beckers, Jörn Viell, Fabian Allan Watt, Valentin Steier, Marcel Mann, Jørgen B. Magnus   +6 more
wiley   +1 more source

Protein Engineering for Industrial Biocatalysis: Principles, Approaches, and Lessons from Engineered PETases

Protein engineering has emerged as a transformative field in industrial biotechnology, enabling the optimization of enzymes to meet stringent industrial demands for stability, specificity, and efficiency.
Evangelos Topakas, Konstantinos Grigorakis, Christina Ferousi   +2 more
core   +1 more source