Results 91 to 100 of about 19,244 (227)
Background Polyploid rice has a high yield potential and excellent nutritional quality. The development of polyploid rice remained critically limited for several decades due to low seed setting rate until the successful breeding of polyploid meiosis ...
Pincang Lv +9 more
doaj +1 more source
The development and optimization of a continuous flow method for the use of ERED enzymes in the reverse mode is presented to convert tetralones into naphthols using air as the terminal oxidant. Both solution‐phase and the immobilized enzyme were explored along with different reactor configurations leading to product yields of up to 83% in short ...
Ruairí Bannon +6 more
wiley +1 more source
A Comparative Biochemical Study of Oleate Hydratases
Four oleate hydratases (Ohys) from diverse homologous families (HFams) were characterized side‐by‐side in terms of expression levels, oligomeric state, flavin adenine dinucleotide (FAD) affinity, thermostability, and activity. A general favorable effect of the reduction of FAD to FADH2 for Ohy activity was demonstrated, with (R)‐10‐hydroxystearic acid (
Maxim van Delft +3 more
wiley +1 more source
Non-Aqueous Biocatalysis in Heterogeneous Solvent Systems
Biocatalysis has become a useful alternative to chemical transformations for the production of a range of compounds with applications in the food, feed, chemical and pharmaceutical industries.
Tej Bhatnagar +5 more
doaj
Extending Cofactor‐Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow
Engineered enzyme fusions bearing covalently tethered PEG–nicotinamide cofactors enable intramolecular cofactor retention and recycling within self‐sufficient biocatalytic nanomachines. These nanomachines support cofactor‐autonomous operation of complex redox multienzyme cascades under continuous‐flow conditions, as demonstrated in a 10‐step glucose‐to‐
Zinnia Dsouza +4 more
wiley +1 more source
A Goodfellowiella coeruleoviolacea Imine Reductase is here reported as a novel enzyme for biocatalytic application in chiral amine synthesis. Deep eutectic solvents have been used to increase substrate loadings, up to 150 mM, and boost enzymatic activity. Reaction scope and scale‐up procedure showcased the protocol applicability.
Federica De Nardi +5 more
wiley +1 more source
A cyanide‐free cascade integrating photocatalysis and biocatalysis is presented. Benzyl alcohols undergo light‐driven oxidation–oximation to form oxime intermediates, which are subsequently converted into benzonitriles through dehydration catalyzed by an engineered aldoxime dehydratase.
Luca Nespoli +3 more
wiley +1 more source
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza +11 more
wiley +1 more source
Biocatalytic structural diversification of saponins in Zygophyllum decumbens: HR-LC-ESI-TOF-MS/MS profiling and bioactivity modulation. [PDF]
Gabr NM +4 more
europepmc +1 more source

