Results 91 to 100 of about 3,482,455 (367)

EC-BLAST: a tool to automatically search and compare enzyme reactions. [PDF]

, 2014
We present EC-BLAST (http://www.ebi.ac.uk/thornton-srv/software/rbl/), an algorithm and Web tool for quantitative similarity searches between enzyme reactions at three levels: bond change, reaction center and reaction structure similarity.
A Dalby, A Theocharidis, AL Cuff, C Jochum, C Steinbeck, DARSD Latino, F Mu, Gemma L Holliday, I Ugi, J Lees, J-L Faulon, Janet M Thornton, K Tipton, L Chen, M Kanehisa, M Kotera, M Leber, Nicholas Furnham, NM O'Boyle, NM O'Boyle, Q-Y Zhang, RHS Thompson, RS Cahn, S Heller, SA Rahman, SA Rahman, Sergio Martinez Cuesta, Syed Asad Rahman, T Sing, V Egelhofer, V Prelog, WL Chen, Y Yamanishi   +32 more
core   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model. [PDF]

, 2017
In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor.
Baar, Keith, Lee-Barthel, Ann, West, Daniel WD   +2 more
core   +2 more sources

An overview on biofuel and biochemical production by photosynthetic microorganisms with understanding of the metabolism and by metabolic engineering together with efficient cultivation and downstream processing

Bioresources and Bioprocessing, 2015
Biofuel and biochemical production by photosynthetic microorganisms such as cyanobacteria and algae is attractive to improve energy security and to reduce CO2 emission, contributing to the environmental problems such as global warming.
Dayanidhi Sarkar, K. Shimizu
semanticscholar   +1 more source

Elucidating the genotype-phenotype map by automatic enumeration and analysis of the phenotypic repertoire. [PDF]

, 2015
BackgroundThe gap between genotype and phenotype is filled by complex biochemical systems most of which are poorly understood. Because these systems are complex, it is widely appreciated that quantitative understanding can only be achieved with the aid ...
Lomnitz, Jason G, Savageau, Michael A
core   +1 more source

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Metabolites, 2015
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
M. C. Lai, Ethan I. Lan
semanticscholar   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Systems Biology Graphical Notation: Entity Relationship language Level 1 (Version 1.2) [PDF]

, 2011
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society would not have evolved at the same pace.
Alice Villeger, Emek Demir, Huaiyu Mi, Nicolas Le Novere, Nicolas Le Novere, Stuart Moodie   +5 more
core   +2 more sources

Phosphate limitation enhances malic acid production on nitrogen-rich molasses with Ustilago trichophora

Biotechnology for Biofuels and Bioproducts
Background An important step in replacing petrochemical products with sustainable, cost-effective alternatives is the use of feedstocks other than, e.g., pure glucose in the fermentative production of platform chemicals.
Luca Antonia Grebe, Philipp Georg Lichtenberg, Katharina Hürter, Eva Forsten, Katharina Miebach, Jochen Büchs, Jørgen Barsett Magnus   +6 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source