Results 111 to 120 of about 261,713 (289)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Adaptive Constrained Independent Vector Analysis: Application to Large-Scale fMRI Analysis

open access: yes, 2020
Functional magnetic resonance imaging (fMRI) provides non-invasive indirect measures of neuronal activation in the brain. Analysis of large-scale fMRI datasets, acquired from a large pool of individuals, has become prominent in recent studies for the ...
Bhinge, Suchita
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

An introduction to Biomodel engineering, illustrated for signal transduction pathways

open access: yes, 2009
BioModel Engineering is the science of designing, constructing and analyzing computational models of biological systems. It is inspired by concepts from software engineering and computing science.
Donaldson, R   +7 more
core   +1 more source

Development of a Cell-Free Protein Expression System Derived from Human Blood Cells

open access: yes, 2020
Recombinant proteins are typically produced using living cells. Alternatively, recombinant proteins can be produced using cellular extracts in a "cell-free" protein expression system.
Burgenson, David
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Chemical engineering journal.

open access: yes
"An international journal of research and development."Place of publication varies.Some issues also have distinctive theme titles.Title from cover.Chemical abstractsTheoretical chemical abstractsSome nos.

core  

A generic approach to behaviour-driven biochemical model construction

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Modelling of biochemical systems has received considerable attention over the last decade from bioengineering, biochemistry, computer science, and ...
Wu, Zujian
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Batch and Continuous Biochemical Reactor Studies Using Mixed Microbial Cultures

open access: yes, 1968
Using soluble organic carbon in the form of glucose as a growth limiting nutrient, the kinetics of mixed microbial populations (mainly bacterial in content) were studied using completely mixed batch and continuous biochemical reactors, in order to ...
Bennett, John
core  

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