Results 111 to 120 of about 557,900 (328)

'BioNessie(G) - a grid enabled biochemical networks simulation environment [PDF]

, 2008
The simulation of biochemical networks provides insight and understanding about the underlying biochemical processes and pathways used by cells and organisms.
Ajayi, O, Gilbert, D, Gu, X, Jiang, J, Liu, X, Sinnott, R   +5 more
core  

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Prediction of Escherichia coli expression performance in microtiter plates by analyzing only the temporal development of scattered light during culture

Journal of Biological Engineering, 2017
Background Escherichia coli is often used for recombinant protein production. The expression of recombinant proteins negatively affects the microbial growth, thus, a balance between protein expression and biomass formation is preferable to reach high ...
Tobias Ladner, Martina Mühlmann, Andreas Schulte, Georg Wandrey, Jochen Büchs   +4 more
doaj   +1 more source

FEBS news biochemical engineering ‐ summer course [PDF]

, 1987

openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Protein engineering loops in aspartic proteinases: site-directed mutagenesis, biochemical characterization and X-ray analysis of chymosin with a replaced loop from rhizopuspepsin [PDF]

, 1996
Philip G. Nugent, Armando Albert, P. Orprayoon, Julie Wilsher, Jim E. Pitts, Tom L. Blundell, V. Dhanaraj   +6 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Biochemical engineering of the N-acyl side chain of sialic acid: biological implications [PDF]

, 2001
Oliver T. Keppler, R. Horstkorte, Michael Pawlita, Carl J. Schmidt, Werner Reutter   +4 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Biochemical Engineering of Cell Surface Sialic Acids Stimulates Axonal Growth [PDF]

, 2002
Bettina Büttner, Christoph Kannicht, Carolin Schmidt, Klemens Löster, Werner Reutter, Hye-Youn Lee, Sabine Nöhring, Rüdiger Horstkorte   +7 more
openalex   +1 more source