Results 31 to 40 of about 1,653,042 (267)

Diagnosis and management of biochemical recurrence in patients with prostate cancer who received definitive treatment

open access: yesUrology Research and Practice, 2019
After definitive treatment, recurrence is seen in some patients, as manifested by a rise in prostate-specific antigen (PSA) before clinical progression.
Hasan Soydan, Kadir Baykal
doaj   +2 more sources

The epiphyseal plate closure phenomena for male and female Japanese quail ( Coturnix coturnix japonica ): histological and biochemical alterations

open access: yesRevista Brasileira de Zootecnia, 2020
This study was conducted to determine the effect of sex on ossification processes in quail by determining the exact closure timing of the epiphyseal plate in the proximal region of the femur.
Zelal Karakoç, Kıvanç İrak
doaj   +1 more source

A comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells. [PDF]

open access: yesPLoS ONE, 2013
The non-receptor tyrosine kinase Src and receptor tyrosine kinase epidermal growth factor receptor (EGFR/ErbB1) have been established as collaborators in cellular signaling and their combined dysregulation plays key roles in human cancers, including ...
Tomáš Helikar   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

ECOLOGICAL ESTIMATES SODIUM CHLORIDE IMPACT ON PHYSIOLOGY OF WHEAT OF CULTURES

open access: yesАлматы технологиялық университетінің хабаршысы, 2021
The article discusses the phenomena of soil salinization in agriculture, causing anotomic changes in the vessels of plant crops, physiological and biochemical changes.
G. S. Sultangazieva   +2 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Pathophysiology of Headaches with a Prominent Vascular Component

open access: yesPain Research and Management, 1996
Vascular changes, whether preliminary or secondary, seem to accompany most headaches. The literature concerning pathophysiological mechanisms in headaches where vascular phenomena are a major, integral part, ie, migraine and cluster headache syndrome, is
Juan A Pareja   +2 more
doaj   +1 more source

Electric Fields at the Lipid Membrane Interface

open access: yesMembranes, 2023
This review presents a comprehensive analysis of electric field distribution at the water–lipid membrane interface in the context of its relationship to various biochemical problems.
Yury A. Ermakov
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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