Results 61 to 70 of about 236,896 (291)

Overview of Numerical Simulation of Solid-State Anaerobic Digestion Considering Hydrodynamic Behaviors, Phenomena of Transfer, Biochemical Kinetics and Statistical Approaches

open access: yesEnergies, 2023
Anaerobic digestion (AD) is a promising way to produce renewable energy. The solid-state anaerobic digestion (SSAD) with a dry matter content more than 15% in the reactors is seeing its increasing potential in biogas plant deployment.
Xiaojun Liu   +4 more
doaj   +1 more source

Minimum Action Path theory reveals the details of stochastic biochemical transitions out of oscillatory cellular states [PDF]

open access: yes, 2017
Cell state determination is the outcome of intrinsically stochastic biochemical reactions. Tran- sitions between such states are studied as noise-driven escape problems in the chemical species space.
Alarcón Cor, Tomás   +5 more
core   +4 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Preterm Birth, From the Biological Knowledges to the Prevention: An Overview

open access: yesMaternal-Fetal Medicine, 2020
. The time of birth is a critical determinant of perinatal and long-term outcomes, and even trans-generational effects. Preterm birth is still the leading cause of infant mortality and morbidity.
Valentina Tosto   +4 more
doaj   +1 more source

Neuronal oxidative injury in the development of the epileptic disease : a potential target for novel therapeutic approaches [PDF]

open access: yes, 2011
Epileptic diseases affect about 50 million people in the world and approximately 30% of patients diagnosed with epilepsy are unresponsive to current medications.
Maio, Roberto di
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Noise-induced Input Dependence in a Convective Unstable Dynamical System

open access: yes, 1998
Unidirectionally coupled dynamical system is studied by focusing on the input (or boundary) dependence. Due to convective instability, noise at an up-flow is spatially amplified to form an oscillation. The response, given by the down-flow dynamics, shows
Fujimoto, Koichi, Kaneko, Kunihiko
core   +1 more source

Global convergence of quorum-sensing networks [PDF]

open access: yes, 2010
In many natural synchronization phenomena, communication between individual elements occurs not directly, but rather through the environment. One of these instances is bacterial quorum sensing, where bacteria release signaling molecules in the ...
Russo, Giovanni   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Robust and Irreversible Development in Cell Society as a General Consequence of Intra-Inter Dynamics

open access: yes, 1999
A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction.
Eigen   +22 more
core   +2 more sources

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