Results 171 to 180 of about 1,905,672 (358)

Biochemical recurrence in prostate cancer: review article

open access: yes, 2007
O câncer de próstata é a segunda neoplasia mais freqüente em homens, e a utilização do PSA levou a um aumento no número de casos diagnosticados com doença clinicamente localizada. A recidiva bioquímica é a elevação dos níveis de PSA em pacientes submetidos a tratamento com finalidade curativa para a doença localizada, na ausência de sinais clínicos ou ...
Fonseca, Roberto Porto   +6 more
openaire   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon   +10 more
wiley   +1 more source

Surface-enhanced Raman spectroscopy before radical prostatectomy predicts biochemical recurrence better than CAPRA-S

open access: yesInternational Journal of Nanomedicine, 2019
Jiahua Pan,1,* Xiaoguang Shao,1,* Yinjie Zhu,1,* Baijun Dong,1 Yanqing Wang,1 Xiaonan Kang,2 Na Chen,3 Zhenyi Chen,3 Shupeng Liu,3 Wei Xue1 1Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127 ...
Pan J   +9 more
doaj  

Impact of Matrix Metalloproteinase-11 Gene Polymorphisms on Biochemical Recurrence and Clinicopathological Characteristics of Prostate Cancer [PDF]

open access: gold, 2020
Chun-Yu Hsieh   +8 more
openalex   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee   +17 more
wiley   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli   +14 more
wiley   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues   +6 more
wiley   +1 more source

High-risk biochemical recurrence in prostate cancer: identification and early intervention strategies. [PDF]

open access: yesFront Urol
Abdelaziz AH   +8 more
europepmc   +1 more source

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