Results 221 to 230 of about 1,905,672 (358)

Biochemical recurrence-free survival after prostate cancer

Reports of Practical Oncology & Radiotherapy, 2013
Alled Comín, L., Laria Font, C., Pérez Pausin, J., Escó Barón, R., Velilla Millán, C., López Mata, M.   +5 more
openaire   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Observational Management for Patients with Biochemical Recurrence Following Radical Prostatectomy, in the Absence of Detectable Disease on Restaging PSMA PET/CT Imaging. [PDF]

Diagnostics (Basel)
de Bie KCC, Mellema JJ, Meijer D, Teunissen FR, van Leeuwen PJ, Oprea-Lager DE, Donswijk ML, van den Bergh RCN, Vis AN.   +8 more
europepmc   +1 more source

Prostate Bed Stereotactic Body Radiation Therapy (PB-SBRT) for Postprostatectomy Biochemical Recurrence: First Toxicity Results of a Phase 1 Dose-Escalation Trial [PDF]

, 2016
Sagus Sampath, Bertram Yuh, Paul Frankel, A. Liu, Peter T. Tsai, P. Twardowski, C.A. Stein, Mark H. Kawachi, Savita Dandapani, Timothy E. Schultheiss, Jeffrey Y.C. Wong   +10 more
openalex   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Impact of positive surgical margin location on biochemical recurrence in pT3 prostate cancer after robot-assisted radical prostatectomy: a retrospective cohort study. [PDF]

BMC Urol
Altay MS, Kocatürk H, Bedir B, Bedir F, Cinislioğlu AE, Yeğen AF, Aydin Ö, Canda AE, Balbay MD.   +8 more
europepmc   +1 more source

A joint frailty model to assess the relationship between time to curative treatment and biochemical recurrence in prostate cancer patients

Abderrahim Oussama Batouche, Denis Rustand, Eugen Czeizler, Håvard Rue, Tuomas Mirtti, Antti Rannikko   +5 more
openalex   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Metastasis-Free Survival in Patients with Biochemical Recurrence After Robot-Assisted Radical Prostatectomy: A Multicenter, Retrospective Cohort Study in Japan (MSUG94 Group). [PDF]

Curr Oncol
Nezasa M, Tomioka M, Tatenuma T, Sasaki T, Ikehata Y, Nakayama A, Toide M, Yoneda T, Sakaguchi K, Makiyama K, Inoue T, Kitamura H, Saito K, Koga F, Urakami S, Koie T.   +15 more
europepmc   +1 more source

Who can benefit from postoperative radiotherapy following biochemical recurrence after radical prostatectomy?—looking for the “Rosetta Stone” of prostate cancer

, 2018
Marco Krengli, Letizia Deantonio, Michele Billia, Alessandro Volpe   +3 more
openalex   +1 more source