Results 241 to 250 of about 360,147 (291)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Genetic architecture of the Sindhi Indian population: a 19X-STR forensic analysis. [PDF]

open access: yesBMC Genomics
Gautam K   +6 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

A haplotype-resolved reference genome for Eucalyptus grandis. [PDF]

open access: yesG3 (Bethesda)
Lötter A   +14 more
europepmc   +1 more source

Genetic variability of the prion protein gene (PRNP) in thin-tailed and fat-tailed sheep. [PDF]

open access: yesOpen Vet J
Wicaksono A   +5 more
europepmc   +1 more source

Common molecular links and therapeutic insights between type 2 diabetes and kidney cancer. [PDF]

open access: yesPLoS One
Ahmmed R   +7 more
europepmc   +1 more source

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