Results 121 to 130 of about 1,957,522 (351)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Significance of the Glutathione-S-Transferase Activity and the Total Thiols Status in Chronic Alcoholics [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2012
Objectives: The present study was conducted to assess the activity of glutathione -S-transferase (GST) and its relationship with total thiols (T-SH) in patients with alcohol liver disease (ALD).
Mamta Singh   +2 more
doaj  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Biochemical measurements of beef are a good predictor of untrained consumer sensory scores across muscles

open access: yesAnimal, 2015
The ability of the biochemical measurements, haem iron, intramuscular fat (IMF%), moisture content, and total, soluble and insoluble collagen contents, to predict untrained consumer sensory scores both across different muscles and within the same muscle ...
S.P.F. Bonny   +5 more
doaj  

Identification of Predictors of Abnormal Calcium, Magnesium and Phosphorus Blood Levels in the Emergency Department: A Retrospective Cohort Study

open access: yesOpen Access Emergency Medicine, 2021
Antoine Lapointe,1 Nikyel Royer Moreau,1 David Simonyan,2 François Rousseau,2 Viviane Mallette,1 Frédérique Préfontaine-Racine,1 Caroline Paquette,1 Myriam Mallet,2 Annie St-Pierre,1 Simon Berthelot1,2 1Département de m&
Lapointe A   +9 more
doaj  

Label-free biochemical quantitative phase imaging with mid-infrared photothermal effect [PDF]

open access: yesarXiv, 2019
Label-free optical imaging is valuable in biology and medicine with its non-destructive property and reduced optical and chemical damages. Quantitative phase (QPI) and molecular vibrational imaging (MVI) are the two most successful label-free methods, providing morphology and biochemistry, respectively, that have pioneered numerous applications along ...
arxiv  

Scientific publications of the Bioscience Program Division. Volume II - Environmental biology [PDF]

open access: yes
Environmental biology bibliography, including citations on biochemistry, radiobiology, and ...
Hong, F., Kulp, L. A.
core   +1 more source

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