Results 61 to 70 of about 55,745 (174)

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

EVALUATION EXTERNE DE LA QUALITE AU LABORATOIRE DE BIOCHIMIE DU CHU TIZI OUZOU

, 2019
Cette étude vise à évaluer les performances de quelques examens biochimiques. Il s’agit d’une étude descriptive menée sur des résultats d’évaluation externe de la qualité « EEQ » et portant sur les résultats de 10 examens courants de biochimie clinique ...
RAHMOUNE, L’hadi Farhat, LASMI, Salah, BENANE, Nouredine   +2 more
core  

Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells

Journal of Lipid Research, 1997
Docosahexaenoic acid (22:6) decreases blood platelet function and is highly concentrated in the brain where its depletion leads to functional impairments.
N Brossard, M Croset, S Normand, J Pousin, J Lecerf, M Laville, J L Tayot, M Lagarde   +7 more
doaj   +1 more source

The Warburg Effect in Yeast: Repression of Mitochondrial Metabolism Is Not a Prerequisite to Promote Cell Proliferation

Frontiers in Oncology, 2020
O. Warburg conducted one of the first studies on tumor energy metabolism. His early discoveries pointed out that cancer cells display a decreased respiration and an increased glycolysis proportional to the increase in their growth rate, suggesting that ...
Cyrielle L. Bouchez, Cyrielle L. Bouchez, Noureddine Hammad, Noureddine Hammad, Sylvain Cuvellier, Sylvain Cuvellier, Stéphane Ransac, Stéphane Ransac, Michel Rigoulet, Michel Rigoulet, Anne Devin, Anne Devin   +11 more
doaj   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Human low density lipoprotein subfractions separated by gradient gel electrophoresis: composition, distribution, and alterations induced by cholesteryl ester transfer protein.

Journal of Lipid Research, 1990
Low density lipoprotein (LDL) subfractions were studied in sera from 208 normolipidemic, 22 hypercholesterolemic, and 33 hypertriglyceridemic subjects.
P Gambert, C Bouzerand-Gambert, A Athias, M Farnier, C Lallemant   +4 more
doaj   +1 more source

Thrombosis in individuals with high oxygen affinity hemoglobin‐associated erythrocytosis: A systematic review and analysis of a national cohort

HemaSphere, Volume 10, Issue 9, September 2026.
Marie Laloi, Nada Maaziz, Victor Bobée, Philippe Joly, Muriel Giansily‐Blaizot, Mathieu Carpentier, Marie‐Pierre Gourin, Sébastien Trouillier, Claire Barro, Charles Dumontet, Clémence Santana, Matthieu Wemeau, Mathilde Hunault, Damien Luque‐Paz, Serge Pissard, Frédéric Galactéros, François Girodon, Patricia Aguilar‐Martinez, Loïc Garcon, Corentin Orvain   +19 more
wiley   +1 more source

Role of cholesteryl ester transfer protein (CETP) in the HDL conversion process as evidenced by using anti-CETP monoclonal antibodies

Journal of Lipid Research, 1990
The implication of cholesteryl ester transfer protein (CETP) in the high density lipoprotein (HDL) conversion process was studied by incubating HDL3 with a purified CETP preparation for 24 h at 37 degrees C.
L Lagrost, P Gambert, V Dangremont, A Athias, C Lallemant   +4 more
doaj   +1 more source

Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.

Journal of Lipid Research, 1990
In cultured pig coronary smooth muscle cells phorbol 12-myristate 13-acetate (PMA) stimulated the conversion of [4-14C]cholesterol into cholesteryl esters and the incorporation of [2-3H]glycerol into triglycerides 6.4- and 4.5-fold, respectively.
M Moinat, JM Chevey, P Muzzin, JP Giacobino, M Kossovsky   +4 more
doaj   +1 more source