Results 51 to 60 of about 18,280 (172)

MAVISp: A modular structure‐based framework for protein variant effects

Protein Science, Volume 35, Issue 5, May 2026.
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi, Mattia Utichi, Kristine Degn, Matteo Tiberti, Ludovica Beltrame, Karolina Krzesińska, Pablo Sánchez‐Izquierdo Besora, Eleni Kiachaki, Simone Scrima, Laura Bauer, Katrine Meldgård, Anna Melidi, Lorenzo Favaro, Anu Oswal, Guglielmo Tedeschi, Terézia Dorčaková, Alberte Heering Estad, Joachim Breitenstein, Jordan Safer, Paraskevi Saridaki, Valentina Sora, Francesca Maselli, Philipp Becker, Jérémy Vinhas, Alberto Pettenella, Matteo Lambrughi, Claudia Cava, Anna Rohlin, Mef Nilbert, Sumaiya Iqbal, Peter Wad Sackett, Burcu Aykac Fas, Elena Papaleo   +32 more
wiley   +1 more source

Diversity, Host Attachment Preferences and Role of Tick Rhipicephalus microplus in the Transmission of Bartonella spp. and Rickettsia spp. in Cattle From Southern Benin

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Ticks infesting cattle in Southern Benin were investigated for diversity, attachment preferences and zoonotic bacteria. Among 2210 ticks collected from 540 cattle, Rhipicephalus microplus predominated (79.6%). Ticks mainly attached to ears, axillae and trunk. PCR detection revealed Bartonella spp. and Rickettsia spp., highlighting veterinary and public
Minassou Juvénal Ahouandjinou, Zul‐kifl Affolabi, Steve Zinsou Hougbe, Koffi Djigbodi Koumodji, Prudenciène A. Agboho, Zinsou Côme Koukpo, Arsène Jacques Fassinou, Saïd Chitou, Linda Towakinou, Filémon Tokponnon, Martin Akogbeto, Razaki A. Ossè   +11 more
wiley   +1 more source

sRNA and cis-antisense sRNA identification in Staphylococcus aureus highlights an unusual sRNA gene cluster with one encoding a secreted peptide

Scientific Reports, 2017
The human pathogen Staphylococcus aureus expresses a set of transcriptional factors and small RNAs (sRNAs) to adapt to environmental variations. Recent harmonization of staphylococcal sRNA data allowed us to search for novel sRNAs using DETR’PROK, a ...
Julie Bronsard, Gaetan Pascreau, Mohamed Sassi, Tony Mauro, Yoann Augagneur, Brice Felden   +5 more
doaj   +1 more source

Longitudinal Study of Plasma NFL and GFAP as Biomarkers of Alcohol Withdrawal–Associated Brain Injury

Addiction Biology, Volume 31, Issue 5, May 2026.
Brain injury could occur within the first days of alcohol withdrawal, especially in patients with severe pharmacological dependence. Plasma NFL and GFAP are promising biomarkers of alcohol withdrawal‐related brain pathology. ABSTRACT Plasma neurofilament light chain (NFL), glial fibrillary acidic protein (GFAP), tau protein and ubiquitin carboxy ...
Virgile Clergue‐Duval, Frank Questel, Alexandra Dereux, Elodie Bouaziz‐Amar, Julien Azuar, Romain Icick, Dorian Rollet, Vanessa Bloch, Jérôme Jeanblanc, Cynthia Marie‐Claire, Jean‐Louis Laplanche, Frank Bellivier, Claire Paquet, Mickael Naassila, Florence Vorspan   +14 more
wiley   +1 more source

Efficacy and safety of once‐weekly insulins in type 2 diabetes: A systematic review and meta‐analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3491-3501, May 2026.
Abstract Aims Once‐weekly (OW) insulins represent a promising strategy to reduce injection burden and improve adherence in type 2 diabetes management. This meta‐analysis aimed to quantify pooled effect sizes for key biological and clinical outcomes, integrating new findings from the five large trials published in 2025.
Olivier Bourron, Damien Denimal
wiley   +1 more source

The Warburg Effect in Yeast: Repression of Mitochondrial Metabolism Is Not a Prerequisite to Promote Cell Proliferation

Frontiers in Oncology, 2020
O. Warburg conducted one of the first studies on tumor energy metabolism. His early discoveries pointed out that cancer cells display a decreased respiration and an increased glycolysis proportional to the increase in their growth rate, suggesting that ...
Cyrielle L. Bouchez, Cyrielle L. Bouchez, Noureddine Hammad, Noureddine Hammad, Sylvain Cuvellier, Sylvain Cuvellier, Stéphane Ransac, Stéphane Ransac, Michel Rigoulet, Michel Rigoulet, Anne Devin, Anne Devin   +11 more
doaj   +1 more source

Human low density lipoprotein subfractions separated by gradient gel electrophoresis: composition, distribution, and alterations induced by cholesteryl ester transfer protein.

Journal of Lipid Research, 1990
Low density lipoprotein (LDL) subfractions were studied in sera from 208 normolipidemic, 22 hypercholesterolemic, and 33 hypertriglyceridemic subjects.
P Gambert, C Bouzerand-Gambert, A Athias, M Farnier, C Lallemant   +4 more
doaj   +1 more source

Role of cholesteryl ester transfer protein (CETP) in the HDL conversion process as evidenced by using anti-CETP monoclonal antibodies

Journal of Lipid Research, 1990
The implication of cholesteryl ester transfer protein (CETP) in the high density lipoprotein (HDL) conversion process was studied by incubating HDL3 with a purified CETP preparation for 24 h at 37 degrees C.
L Lagrost, P Gambert, V Dangremont, A Athias, C Lallemant   +4 more
doaj   +1 more source

Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.

Journal of Lipid Research, 1990
In cultured pig coronary smooth muscle cells phorbol 12-myristate 13-acetate (PMA) stimulated the conversion of [4-14C]cholesterol into cholesteryl esters and the incorporation of [2-3H]glycerol into triglycerides 6.4- and 4.5-fold, respectively.
M Moinat, JM Chevey, P Muzzin, JP Giacobino, M Kossovsky   +4 more
doaj   +1 more source

Thyroid function in the first trimester of pregnancy

Journal de la Faculté de Médecine d'Oran, 2019
Introduction - Dysthyroidism represents the second most frequent pathologies after diabetes in pregnant women. The thyroid undergoes many physiological changes during pregnancy and its functional activity increases by 50%.
Hanachi Sabah, Karima SIFI, Yamina BOUCHEDJRA, Khalida BOUDAOUD, Salim ZEKRI, Karima BENEMBAREK, Noureddine ABADI   +6 more
doaj