Results 31 to 40 of about 18,280 (172)

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

American Journal of Hematology, Volume 101, Issue 7, Page 1706-1716, July 2026.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger, Nicolas Hebert, Laura Bencheikh, Vincent Malcor Deydier de Pierrefeu, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Sandia Adypagavane, Meghan Perkins, Laura Matabishi‐Bibi, France Pirenne, Claire Berquet, Stephane Moutereau, Serge Pissard, Frédéric Galactéros, Michael C. Marden, Pablo Bartolucci   +14 more
wiley   +1 more source

Données récentes touchant à la nutrition et appliquées à l'alimentation animale

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1955
Aucun résumé disponible.
R. Ferrando
doaj   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

In vitro analytical interference of L-ascorbic acid in enzymatic assays based on the Trinder reaction [PDF]

Batna Journal of Medical Sciences
Introduction: Ascorbic acid, a water-soluble compound with antioxidant properties, can interfere with several enzymatic methods used in clinical biochemistry.
Mohamed Abdou OUDRER, Oussama FERHAT, Ikram TERBECHE, Mustapha ZENDJABIL, Amel Soulef SAADI- OUSLIM   +4 more
doaj   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

BMC Biotechnology, 2018
Background Dicer is a 219-kDa protein that plays key roles in gene regulation, particularly as the ribonuclease III enzyme responsible for cleaving precursor miRNA substrates.
Jonathan Bouvette, Dursun Nizam Korkut, Aurélien Fouillen, Soumiya Amellah, Antonio Nanci, Yves Durocher, James G. Omichinski, Pascale Legault   +7 more
doaj   +1 more source

First‐Trimester Down Syndrome Screening in Renal‐Transplanted Pregnant Women: Blood Creatinine Levels Impact False‐Positive Rate

Prenatal Diagnosis, Volume 46, Issue 7, Page 993-999, June 2026.
ABSTRACT Objective Over the past few decades, several thousand pregnancies following kidney transplantation have been monitored but few studies have reported on first‐trimester Down syndrome screening. This study aimed to assess the performance of such screening and its relationship with renal function.
Clément Burgy, Lisa Chanourdie, Béatrice Guyard‐Boileau, Anne‐Laure Hebral, Annelise Genoux, Marie‐Sophie Combis, Paul Guerby, Christophe Vayssiere, Safouane M. Hamdi   +8 more
wiley   +1 more source

Correlation between apolipoprotein A-IV and triglyceride concentrations in human sera.

Journal of Lipid Research, 1989
Apolipoprotein A-IV concentration was measured by a newly developed competitive enzyme immunoassay in sera from fasted human subjects (n = 105) whose triglyceride concentrations ranged from 20 to 474 mg/dl (total cholesterol below 260 mg/dl) and in which
L Lagrost, P Gambert, S Meunier, P Morgado, J Desgres, P d'Athis, C Lallemant   +6 more
doaj   +1 more source

External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV‐Infected Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Cabotegravir (CAB), combined with rilpivirine, is the first long‐acting injectable therapy approved for HIV‐1 maintenance treatment. While adherence and patient satisfaction have been improved, pharmacokinetic (PK) variability remains a concern.
Quentin Renou, Nadège Néant, Alexandre Destere, Jennifer Lagoutte‐Renosi, Matthieu Grégoire, François Parant, Sébastien Lalanne, Florian Lemaitre, Peggy Gandia, Nicolas Venisse, Stéphane Bouchet, Minh P. Lê, Patrice Muret, Gilles Peytavin, Caroline Solas, Sihem Benaboud, the CARLA Study Group, Benoît Bailly, Vincent Gendrin, Timothhee Klopenstein, Souheil Zayet, Quentin Lepiller, Fabienne Bozon, Anne‐Sophie Brunel, Bruno Hoen, Laurent Hustache‐Mathieu, Camille Tumiotto, Mojgane Hemssamfar, Fabrice Bonnet, Ali Si‐Mohammed, Lionel Piroth, Marielle Buisson, Sophie Mahy, Michel Duong, Vinca Icard, Mary‐Anne Trabaud, Dulce Alfaiate, Agathe Becker, Evelyne Braun, Florence Brunel, Matthieu Godinot, Thomas Perpoint, Clément Javaux, Céline Boschi, Philippe Colson, Anne Motte, Véronique Obry‐Roguet, Sylvie Brégigeon, Olivia Faucher‐Zaegel, Hélène Laroche, Maeva Dos Santos, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Amélie Ménard, Matthieu Million, Patrick Philibert, Christina Psomas, Jakub Kowalczyk, Simona‐Loredana Berbescu, Catherine Michel, Elisabeth André‐Garnier, Thomas Drumel, Clotilde Allavena, Eric Billaud, Sabelline Bouchez, Cécile Brunet‐Cartier, Colin Deschanvres, François Raffi, Véronique Reliquet, Gwennaelle Querne, Cecile Mear‐Passard, Antoine Asquier, Charlotte Moyon, Virginie Beslon, Lio Collias, Anne‐Geneviève Marcelin, Vincent Calvez, Diane Descamps, Valentine Ferré, Yazdanpanah Yazdan, Jade Ghosn, Valérie Pourcher, Marc‐Antoine Valantin, Gwenaël Le Moal, David Plainchamp, Anne Maillard, François Benezit, Cédric Arvieux, Pierre Gantner, Christine Cheneau, Axel Ursenbach, Baptiste Hoellinger, Céline Melounou, David Rey, Yves Hansmann   +95 more
wiley   +1 more source

Genetic Predisposition to Diabetic Nephropathy: Role of I/D ACE Gene Polymorphism

Journal de la Faculté de Médecine d'Oran, 2022
Introduction - Diabetic nephropathy is the leading cause of chronic kidney disease and the most common and serious complication of diabetes. Its exact pathogenesis is complex and not completely elucidated.
Sabah HANACHI, Karima SIFI, Khalida BOUDAOUD, Salim ZEKRI, Hanane HOUAMEL, Soumia HASSINI, Karima BENEMBAREK   +6 more
doaj