Effects of repeated exposure to ozonated water on hair fibre structure and integrity: Part I
Repeated exposure to ozonated water caused cumulative oxidative changes in hair, altering structural integrity, thermal behaviour and mechanical properties. The findings reveal a distinct ozone‐induced damage profile that progresses beyond the cuticle, challenging claims of hair‐revitalizing benefits. Abstract Objective Ozone has recently been marketed
Pedro Augusto Laurindo Igreja Marrafa +5 more
wiley +1 more source
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff +6 more
wiley +1 more source
Macromolecules and Enzymes: The Geneva Heritage from Kurt H. Meyer and Edmond H. Fischer
On the 26th May 2009, Edmond Fischer, winner with Ed Krebs of the Nobel prize in physiology or medicine in 1992, and his colleague at the time of his research activities at the Ecole de chimie of the University of Geneva, Alfred Piguet, met with
Edmond H. Fischer, Alfred Piguet
doaj +1 more source
Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
In vitro analytical interference of L-ascorbic acid in enzymatic assays based on the Trinder reaction [PDF]
Introduction: Ascorbic acid, a water-soluble compound with antioxidant properties, can interfere with several enzymatic methods used in clinical biochemistry.
Mohamed Abdou OUDRER +4 more
doaj +1 more source
A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger +14 more
wiley +1 more source
Correlation between apolipoprotein A-IV and triglyceride concentrations in human sera.
Apolipoprotein A-IV concentration was measured by a newly developed competitive enzyme immunoassay in sera from fasted human subjects (n = 105) whose triglyceride concentrations ranged from 20 to 474 mg/dl (total cholesterol below 260 mg/dl) and in which
L Lagrost +6 more
doaj +1 more source
An update on the landscape of collagen bioactive fragments
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension
Background Dicer is a 219-kDa protein that plays key roles in gene regulation, particularly as the ribonuclease III enzyme responsible for cleaving precursor miRNA substrates.
Jonathan Bouvette +7 more
doaj +1 more source
Genetic Predisposition to Diabetic Nephropathy: Role of I/D ACE Gene Polymorphism
Introduction - Diabetic nephropathy is the leading cause of chronic kidney disease and the most common and serious complication of diabetes. Its exact pathogenesis is complex and not completely elucidated.
Sabah HANACHI +6 more
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