Results 41 to 50 of about 18,321 (168)

Effets des pesticides sur la biochimie de la vigne

OENO One, 1970
La thèse récente (1969) de F. CHABOUSSOU (Station de Zoologie agricole du Sud-Ouest, INRA) étudie certains « déséquilibres biologiques », particulièrement les pullulations d'Acariens sur vigne, à la suite de certains traitements pesticides (insecticides ...
Jean RIBEREAU-GAYON
doaj   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Biochimie cellulaire

, 1974
La révolution moléculaire en biologie comprend quatre volets : l’identification chimique du matériel héréditaire en tant qu’acide nucléique polymérisé, l’élucidation des structures des macromolécules biologiques, la preuve que la structure et la biosynthèse des protéines – en particulier des enzymes – sont gouvernées par des gènes spécifiques ; plus ...
  +5 more sources

First‐Trimester Down Syndrome Screening in Renal‐Transplanted Pregnant Women: Blood Creatinine Levels Impact False‐Positive Rate

Prenatal Diagnosis, Volume 46, Issue 7, Page 993-999, June 2026.
ABSTRACT Objective Over the past few decades, several thousand pregnancies following kidney transplantation have been monitored but few studies have reported on first‐trimester Down syndrome screening. This study aimed to assess the performance of such screening and its relationship with renal function.
Clément Burgy, Lisa Chanourdie, Béatrice Guyard‐Boileau, Anne‐Laure Hebral, Annelise Genoux, Marie‐Sophie Combis, Paul Guerby, Christophe Vayssiere, Safouane M. Hamdi   +8 more
wiley   +1 more source

DNA recovery from used malaria RDT to detect Plasmodium species and to assess Plasmodium falciparum genetic diversity: a pilot study in Madagascar

Malaria Journal, 2022
Background Rapid diagnostic tests (RDT) are widely used for malaria diagnosis in Madagascar, where Plasmodium falciparum is the predominant species. Molecular diagnosis is essential for malaria surveillance, but requires additional blood samples for DNA ...
Voahangy Hanitriniaina I. Andrianaranjaka, Elisabeth Ravaoarisoa, Tovonahary A. Rakotomanga, Fanomezantsoa Ralinoro, Danielle A. Doll Rakoto, Ranjàna H. Randrianarivo, Victor Jeannoda, Arsène Ratsimbasoa   +7 more
doaj   +1 more source

Deep intronic ANK1 variants causing pseudo‐exon inclusion in hereditary spherocytosis: Whole‐genome sequencing and functional assessment

British Journal of Haematology, EarlyView.
Victor Marin, Alexandre Janin, Céline Renoux, Yoann Huguenin, AURAGEN consortium, Stéphanie Dulucq, Louis Lebreton, Philippe Joly, Julian Boutin   +8 more
wiley   +1 more source

External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV‐Infected Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Cabotegravir (CAB), combined with rilpivirine, is the first long‐acting injectable therapy approved for HIV‐1 maintenance treatment. While adherence and patient satisfaction have been improved, pharmacokinetic (PK) variability remains a concern.
Quentin Renou, Nadège Néant, Alexandre Destere, Jennifer Lagoutte‐Renosi, Matthieu Grégoire, François Parant, Sébastien Lalanne, Florian Lemaitre, Peggy Gandia, Nicolas Venisse, Stéphane Bouchet, Minh P. Lê, Patrice Muret, Gilles Peytavin, Caroline Solas, Sihem Benaboud, the CARLA Study Group, Benoît Bailly, Vincent Gendrin, Timothhee Klopenstein, Souheil Zayet, Quentin Lepiller, Fabienne Bozon, Anne‐Sophie Brunel, Bruno Hoen, Laurent Hustache‐Mathieu, Camille Tumiotto, Mojgane Hemssamfar, Fabrice Bonnet, Ali Si‐Mohammed, Lionel Piroth, Marielle Buisson, Sophie Mahy, Michel Duong, Vinca Icard, Mary‐Anne Trabaud, Dulce Alfaiate, Agathe Becker, Evelyne Braun, Florence Brunel, Matthieu Godinot, Thomas Perpoint, Clément Javaux, Céline Boschi, Philippe Colson, Anne Motte, Véronique Obry‐Roguet, Sylvie Brégigeon, Olivia Faucher‐Zaegel, Hélène Laroche, Maeva Dos Santos, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Amélie Ménard, Matthieu Million, Patrick Philibert, Christina Psomas, Jakub Kowalczyk, Simona‐Loredana Berbescu, Catherine Michel, Elisabeth André‐Garnier, Thomas Drumel, Clotilde Allavena, Eric Billaud, Sabelline Bouchez, Cécile Brunet‐Cartier, Colin Deschanvres, François Raffi, Véronique Reliquet, Gwennaelle Querne, Cecile Mear‐Passard, Antoine Asquier, Charlotte Moyon, Virginie Beslon, Lio Collias, Anne‐Geneviève Marcelin, Vincent Calvez, Diane Descamps, Valentine Ferré, Yazdanpanah Yazdan, Jade Ghosn, Valérie Pourcher, Marc‐Antoine Valantin, Gwenaël Le Moal, David Plainchamp, Anne Maillard, François Benezit, Cédric Arvieux, Pierre Gantner, Christine Cheneau, Axel Ursenbach, Baptiste Hoellinger, Céline Melounou, David Rey, Yves Hansmann   +95 more
wiley   +1 more source

Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux, William Laine, Patrice Maboudou, Jérôme Kluza, Marie‐Amandine Bonte, Flore Gouel, David Devos, Philippe Marchetti, Jean‐Christophe Devedjian   +8 more
wiley   +1 more source

Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells

Journal of Lipid Research, 1997
Docosahexaenoic acid (22:6) decreases blood platelet function and is highly concentrated in the brain where its depletion leads to functional impairments.
N Brossard, M Croset, S Normand, J Pousin, J Lecerf, M Laville, J L Tayot, M Lagarde   +7 more
doaj   +1 more source