Nanozymes Integrated Biochips Toward Smart Detection System [PDF]
Nanozyme integrated‐biochip systems merge the robust catalytic properties of nanozymes with the portability capabilities of biochips, which have demonstrated significant potential for molecular identification and diagnostic applications.
Dongyu Chen +10 more
doaj +2 more sources
Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip. [PDF]
Microfluidic bioartificial organs allow the reproduction of in vivo-like properties such as cell culture in a 3D dynamical micro environment. In this work, we established a method and a protocol for performing a toxicogenomic analysis of HepG2/C3A ...
Jean Matthieu Prot +7 more
doaj +3 more sources
Comparison of BIOCHIP Mosaic Based Indirect Immunofluorescence and Oral Direct Immunofluorescence in Patients with Oral Mucosal Pemphigus [PDF]
Background: Oral mucosal lesions in pemphigus vulgaris may precede cutaneous lesions and can cause diagnostic confusion. Diagnosis can be made by histopathology, direct immunofluorescence (DIF), and indirect immunofluorescence (IIF).
Amrithaa Muralitharan +2 more
doaj +2 more sources
Application and prospects of lung organ-on-a-chip in the development of new drugs [PDF]
Respiratory disease, such as lung cancer, is a major risk factor that seriously endangers human health. In the development of new drugs, conventional preclinical and clinical testing stages rely on cell culture and animal experiment.
Jun Su +5 more
doaj +2 more sources
Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov +8 more
doaj +3 more sources
A microfluidic biochip for the nanoporation of living cells [PDF]
International audienceThis paper deals with the development of a microfluidic biochip for the exposure of living cells to nanosecond pulsed electric fields (nsPEF). When exposed to ultra short electric pulses (typical duration of 3-10ns), disturbances on
Claire Dalmay +2 more
exaly +3 more sources
Concordance of Biochip-Based and LC-MS/MS Methods in Urine and Blood Samples in Screening for Amphetamine and Methamphetamine [PDF]
Objectives: This study aimed to evaluate the efficacy and reliability of LC-MS/MS and biochip-based screening in detecting narcotics from blood and urine samples.
Murat Akbaba, Aysun Baransel Isir
doaj +2 more sources
Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip [PDF]
The emergence of pathogens resistant to existing antimicrobial drugs is a growing worldwide health crisis that threatens a return to the pre-antibiotic era. To decrease the overuse of antibiotics, molecular diagnostics systems are needed that can rapidly
Arjang Hassibi +2 more
exaly +4 more sources
Quantitative detection of circulating MT-ND1 as a potential biomarker for colorectal cancer
Liquid biopsy represents a diagnostic and monitoring tool and the circulating cell-free mitochondrial DNA (mtDNA) plays a vital role in tumor diagnosis and dynamic assessment.
Yichun Xu +8 more
doaj +1 more source
Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane-protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented.
Ye Fang +6 more
openaire +3 more sources

