Results 1 to 10 of about 22,124 (244)

Nanozymes Integrated Biochips Toward Smart Detection System [PDF]

open access: yesAdvanced Science
Nanozyme integrated‐biochip systems merge the robust catalytic properties of nanozymes with the portability capabilities of biochips, which have demonstrated significant potential for molecular identification and diagnostic applications.
Dongyu Chen   +10 more
doaj   +2 more sources

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip. [PDF]

open access: goldPLoS ONE, 2011
Microfluidic bioartificial organs allow the reproduction of in vivo-like properties such as cell culture in a 3D dynamical micro environment. In this work, we established a method and a protocol for performing a toxicogenomic analysis of HepG2/C3A ...
Jean Matthieu Prot   +7 more
doaj   +3 more sources

Comparison of BIOCHIP Mosaic Based Indirect Immunofluorescence and Oral Direct Immunofluorescence in Patients with Oral Mucosal Pemphigus [PDF]

open access: yesIndian Dermatology Online Journal
Background: Oral mucosal lesions in pemphigus vulgaris may precede cutaneous lesions and can cause diagnostic confusion. Diagnosis can be made by histopathology, direct immunofluorescence (DIF), and indirect immunofluorescence (IIF).
Amrithaa Muralitharan   +2 more
doaj   +2 more sources

Application and prospects of lung organ-on-a-chip in the development of new drugs [PDF]

open access: yesBioMedical Engineering OnLine
Respiratory disease, such as lung cancer, is a major risk factor that seriously endangers human health. In the development of new drugs, conventional preclinical and clinical testing stages rely on cell culture and animal experiment.
Jun Su   +5 more
doaj   +2 more sources

Development of DNA-Biochip for Identification of Influenza A Virus Subtypes

open access: diamondПроблемы особо опасных инфекций, 2012
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov   +8 more
doaj   +3 more sources

A microfluidic biochip for the nanoporation of living cells [PDF]

open access: yesBiosensors and Bioelectronics, 2011
International audienceThis paper deals with the development of a microfluidic biochip for the exposure of living cells to nanosecond pulsed electric fields (nsPEF). When exposed to ultra short electric pulses (typical duration of 3-10ns), disturbances on
Claire Dalmay   +2 more
exaly   +3 more sources

Concordance of Biochip-Based and LC-MS/MS Methods in Urine and Blood Samples in Screening for Amphetamine and Methamphetamine [PDF]

open access: yesDiagnostics
Objectives: This study aimed to evaluate the efficacy and reliability of LC-MS/MS and biochip-based screening in detecting narcotics from blood and urine samples.
Murat Akbaba, Aysun Baransel Isir
doaj   +2 more sources

Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip [PDF]

open access: yesNature Biotechnology, 2018
The emergence of pathogens resistant to existing antimicrobial drugs is a growing worldwide health crisis that threatens a return to the pre-antibiotic era. To decrease the overuse of antibiotics, molecular diagnostics systems are needed that can rapidly
Arjang Hassibi   +2 more
exaly   +4 more sources

Quantitative detection of circulating MT-ND1 as a potential biomarker for colorectal cancer

open access: yesBiomolecules & Biomedicine, 2021
Liquid biopsy represents a diagnostic and monitoring tool and the circulating cell-free mitochondrial DNA (mtDNA) plays a vital role in tumor diagnosis and dynamic assessment.
Yichun Xu   +8 more
doaj   +1 more source

Membrane Biochips [PDF]

open access: yesBioTechniques, 2002
Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane-protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented.
Ye Fang   +6 more
openaire   +3 more sources

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